Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | ZSTK474 | 3 | 72 | 1.0 | 1793.5 | 4157.8 | 571.3 | 0.0 | 0.491 | 0.431 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.32 | 2537.5 | 4157.8 | 571.3 | -0.495 | 0.683 | 0.610 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.1 | 3278.3 | 4157.8 | 571.3 | -1.0 | 0.841 | 0.788 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.032 | 3808.3 | 4157.8 | 571.3 | -1.49 | 0.940 | 0.916 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.001 | 4138.3 | 4157.8 | 571.3 | -3.0 | 0.997 | 0.995 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 3.2 | 1237.3 | 4157.8 | 571.3 | 0.505 | 0.310 | 0.298 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.01 | 4039.0 | 4157.8 | 571.3 | -2.0 | 0.980 | 0.971 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 3 | 72 | 0.0032 | 4190.3 | 4157.8 | 571.3 | -2.49 | 1.010 | 1.010 | 2.863 | Hs578T ZSTK474 3 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.001 | 3461.3 | 3668.0 | 624.7 | -3.0 | 0.955 | 0.944 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.032 | 3160.0 | 3668.0 | 624.7 | -1.49 | 0.887 | 0.862 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.32 | 2154.3 | 3668.0 | 624.7 | -0.495 | 0.624 | 0.587 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.1 | 2555.5 | 3668.0 | 624.7 | -1.0 | 0.736 | 0.697 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 1.0 | 1628.5 | 3668.0 | 624.7 | 0.0 | 0.455 | 0.444 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 3.2 | 968.8 | 3668.0 | 624.7 | 0.505 | 0.187 | 0.264 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.0032 | 3474.8 | 3668.0 | 624.7 | -2.49 | 0.958 | 0.947 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 2 | 72 | 0.01 | 3360.0 | 3668.0 | 624.7 | -2.0 | 0.932 | 0.916 | 2.554 | Hs578T ZSTK474 2 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.32 | 1950.0 | 3415.3 | 873.1 | -0.495 | 0.504 | 0.571 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.032 | 3062.8 | 3415.3 | 873.1 | -1.49 | 0.892 | 0.897 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.1 | 2329.3 | 3415.3 | 873.1 | -1.0 | 0.647 | 0.682 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.001 | 3593.3 | 3415.3 | 873.1 | -3.0 | 1.050 | 1.050 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.0032 | 3578.3 | 3415.3 | 873.1 | -2.49 | 1.050 | 1.050 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 3.2 | 1124.0 | 3415.3 | 873.1 | 0.505 | 0.137 | 0.329 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 1.0 | 1627.5 | 3415.3 | 873.1 | 0.0 | 0.372 | 0.477 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | ZSTK474 | 1 | 72 | 0.01 | 3371.8 | 3415.3 | 873.1 | -2.0 | 0.987 | 0.987 | 1.968 | Hs578T ZSTK474 1 |
| Hs 578T | XL147 | 3 | 72 | 0.1 | 4330.0 | 4203.0 | 571.3 | -1.0 | 1.020 | 1.030 | 2.879 | Hs578T XL147 3 |