Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | AS605240 | 1 | 72 | 0.01 | 6095.5 | 6371.0 | 1443.3 | -2.0 | 0.959 | 0.957 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 1.0 | 5369.8 | 6371.0 | 1443.3 | 0.0 | 0.847 | 0.843 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.1 | 5634.5 | 6371.0 | 1443.3 | -1.0 | 0.889 | 0.884 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.001 | 5834.8 | 6371.0 | 1443.3 | -3.0 | 0.920 | 0.916 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.32 | 5530.8 | 6371.0 | 1443.3 | -0.495 | 0.872 | 0.868 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.032 | 5869.3 | 6371.0 | 1443.3 | -1.49 | 0.925 | 0.921 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 0.0032 | 6003.8 | 6371.0 | 1443.3 | -2.49 | 0.945 | 0.942 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 1 | 72 | 3.2 | 5187.0 | 6371.0 | 1443.3 | 0.505 | 0.817 | 0.814 | 2.142 | BT20 AS605240 0 1 |
| BT-20 | AS605240 | 2 | 72 | 3.2 | 2797.5 | 3661.0 | 1018.6 | 0.505 | 0.729 | 0.764 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.01 | 3080.3 | 3661.0 | 1018.6 | -2.0 | 0.821 | 0.841 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.001 | 3107.0 | 3661.0 | 1018.6 | -3.0 | 0.830 | 0.849 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.032 | 3049.3 | 3661.0 | 1018.6 | -1.49 | 0.811 | 0.833 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.32 | 3018.5 | 3661.0 | 1018.6 | -0.495 | 0.801 | 0.825 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.1 | 2935.5 | 3661.0 | 1018.6 | -1.0 | 0.774 | 0.802 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 1.0 | 2828.3 | 3661.0 | 1018.6 | 0.0 | 0.739 | 0.773 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 2 | 72 | 0.0032 | 3179.8 | 3661.0 | 1018.6 | -2.49 | 0.853 | 0.869 | 1.846 | BT20 AS605240 0 2 |
| BT-20 | AS605240 | 3 | 72 | 0.1 | 3148.5 | 3575.0 | 586.9 | -1.0 | 0.905 | 0.881 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.32 | 3050.3 | 3575.0 | 586.9 | -0.495 | 0.882 | 0.853 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.001 | 3319.5 | 3575.0 | 586.9 | -3.0 | 0.944 | 0.929 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.032 | 3388.8 | 3575.0 | 586.9 | -1.49 | 0.959 | 0.948 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 1.0 | 2935.8 | 3575.0 | 586.9 | 0.0 | 0.854 | 0.821 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.0032 | 3254.5 | 3575.0 | 586.9 | -2.49 | 0.929 | 0.910 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 0.01 | 3575.3 | 3575.0 | 586.9 | -2.0 | 1.000 | 1.000 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AS605240 | 3 | 72 | 3.2 | 2896.3 | 3575.0 | 586.9 | 0.505 | 0.845 | 0.810 | 2.607 | BT20 AS605240 0 3 |
| BT-20 | AZD-6482 | 1 | 72 | 1.0 | 3655.0 | 5948.8 | 1443.3 | 0.0 | 0.576 | 0.614 | 2.043 | BT20 AZD6482 0 1 |