Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | PIK-93 | 1 | 72 | 0.32 | 5519.0 | 5875.8 | 1443.3 | -0.495 | 0.939 | 0.939 | 2.025 | BT20 PIK93 0 1 |
| BT-20 | PIK-93 | 1 | 72 | 1.0 | 4892.3 | 5875.8 | 1443.3 | 0.0 | 0.827 | 0.833 | 2.025 | BT20 PIK93 0 1 |
| BT-20 | PIK-93 | 1 | 72 | 3.2 | 2878.0 | 5875.8 | 1443.3 | 0.505 | 0.406 | 0.490 | 2.025 | BT20 PIK93 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.001 | 3625.0 | 5856.5 | 1443.3 | -3.0 | 0.577 | 0.619 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.0032 | 3775.5 | 5856.5 | 1443.3 | -2.49 | 0.609 | 0.645 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.01 | 3763.8 | 5856.5 | 1443.3 | -2.0 | 0.607 | 0.643 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.032 | 3662.3 | 5856.5 | 1443.3 | -1.49 | 0.585 | 0.625 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.1 | 3647.3 | 5856.5 | 1443.3 | -1.0 | 0.582 | 0.623 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 0.32 | 3778.3 | 5856.5 | 1443.3 | -0.495 | 0.610 | 0.645 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 1.0 | 3619.3 | 5856.5 | 1443.3 | 0.0 | 0.576 | 0.618 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | Sirolimus | 1 | 72 | 3.2 | 3597.5 | 5856.5 | 1443.3 | 0.505 | 0.571 | 0.614 | 2.021 | BT20 Rapamycin 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.001 | 5503.5 | 5723.8 | 1443.3 | -3.0 | 0.961 | 0.962 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.0032 | 5510.0 | 5723.8 | 1443.3 | -2.49 | 0.962 | 0.963 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.01 | 5832.0 | 5723.8 | 1443.3 | -2.0 | 1.020 | 1.020 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.032 | 5704.0 | 5723.8 | 1443.3 | -1.49 | 0.997 | 0.997 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.1 | 5830.8 | 5723.8 | 1443.3 | -1.0 | 1.020 | 1.020 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 0.32 | 5838.0 | 5723.8 | 1443.3 | -0.495 | 1.020 | 1.020 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 1.0 | 5819.3 | 5723.8 | 1443.3 | 0.0 | 1.020 | 1.020 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | TGX221 | 1 | 72 | 3.2 | 5857.5 | 5723.8 | 1443.3 | 0.505 | 1.020 | 1.020 | 1.988 | BT20 TGX221 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.001 | 5232.8 | 5863.3 | 1443.3 | -3.0 | 0.891 | 0.892 | 2.022 | BT20 Torin1 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.0032 | 5036.3 | 5863.3 | 1443.3 | -2.49 | 0.855 | 0.859 | 2.022 | BT20 Torin1 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.01 | 4237.5 | 5863.3 | 1443.3 | -2.0 | 0.703 | 0.723 | 2.022 | BT20 Torin1 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.032 | 3317.0 | 5863.3 | 1443.3 | -1.49 | 0.509 | 0.566 | 2.022 | BT20 Torin1 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.1 | 2475.0 | 5863.3 | 1443.3 | -1.0 | 0.306 | 0.422 | 2.022 | BT20 Torin1 0 1 |
| BT-20 | Torin1 | 1 | 72 | 0.32 | 2025.3 | 5863.3 | 1443.3 | -0.495 | 0.182 | 0.345 | 2.022 | BT20 Torin1 0 1 |