LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180614_BG_03 | 12830 | 0.0164 | 54 | 157 | 11 | 6 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_6 | 211 | 0.0162 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00382 | 0.8708 |
| Alpelisib | 180614_BG_04 | 12326 | 0.0229 | 145 | 141 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_7 | 286 | 0.0227 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00268 | 0.8533 |
| Alpelisib | 180614_BG_04 | 13137 | 0.0253 | 156 | 180 | 5 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_8 | 336 | 0.0249 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00494 | 0.8812 |
| Alpelisib | 180614_BG_04 | 12183 | 0.0243 | 128 | 171 | 7 | 18 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_9 | 299 | 0.0240 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00396 | 0.8482 |
| Alpelisib | 180614_BG_02 | 9366 | 0.0236 | 56 | 166 | 6 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_1 | 222 | 0.0232 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00316 | 0.7376 |
| Alpelisib | 180614_BG_02 | 9989 | 0.0227 | 56 | 172 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 228 | 0.0223 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00232 | 0.7641 |
| Alpelisib | 180614_BG_02 | 9583 | 0.0225 | 50 | 167 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 217 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00215 | 0.7470 |
| Alpelisib | 180614_BG_03 | 10866 | 0.0190 | 65 | 143 | 8 | 4 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 208 | 0.0188 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00121 | 0.7993 |
| Alpelisib | 180614_BG_03 | 10116 | 0.0179 | 57 | 125 | 10 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 182 | 0.0177 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00232 | 0.7693 |
| Alpelisib | 180614_BG_03 | 10716 | 0.0173 | 65 | 122 | 11 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 187 | 0.0172 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00284 | 0.7934 |
| Alpelisib | 180614_BG_04 | 9712 | 0.0341 | 191 | 147 | 5 | 19 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 338 | 0.0336 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01364 | 0.7525 |
| Alpelisib | 180614_BG_04 | 11300 | 0.0228 | 124 | 136 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 260 | 0.0225 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00250 | 0.8159 |
| Alpelisib | 180614_BG_04 | 10966 | 0.0276 | 140 | 167 | 14 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_9 | 307 | 0.0272 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00724 | 0.8031 |
| Alpelisib | 180614_BG_02 | 5374 | 0.0236 | 46 | 82 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 128 | 0.0233 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00327 | 0.5253 |
| Alpelisib | 180614_BG_02 | 5565 | 0.0221 | 45 | 79 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 124 | 0.0218 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00180 | 0.5378 |
| Alpelisib | 180614_BG_02 | 5488 | 0.0212 | 27 | 90 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 117 | 0.0209 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00088 | 0.5328 |
| Alpelisib | 180614_BG_03 | 5521 | 0.0329 | 104 | 81 | 3 | 11 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 185 | 0.0324 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01243 | 0.5350 |
| Alpelisib | 180614_BG_03 | 5617 | 0.0136 | 26 | 51 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 77 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00647 | 0.5412 |
| Alpelisib | 180614_BG_03 | 5511 | 0.0245 | 70 | 67 | 6 | 16 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 137 | 0.0243 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00426 | 0.5343 |
| Alpelisib | 180614_BG_04 | 7371 | 0.0251 | 90 | 97 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 187 | 0.0247 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00475 | 0.6427 |
| Alpelisib | 180614_BG_04 | 6752 | 0.0288 | 113 | 85 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 198 | 0.0285 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00849 | 0.6092 |
| Alpelisib | 180614_BG_04 | 6841 | 0.0354 | 169 | 79 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 248 | 0.0350 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01499 | 0.6142 |
| Dasatinib | 180614_BG_02 | 17360 | 0.0204 | 53 | 303 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 356 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00010 | 1.0084 |
| Dasatinib | 180614_BG_02 | 17249 | 0.0161 | 33 | 245 | 10 | 17 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 278 | 0.0159 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00413 | 1.0053 |
| Dasatinib | 180614_BG_02 | 16674 | 0.0159 | 47 | 219 | 12 | 4 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 266 | 0.0157 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00429 | 0.9894 |