LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
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Taxol | 180619_MC_10 | 11762 | 0.0245 | 57 | 233 | 14 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_3 | 290 | 0.0241 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00099 | 0.8943 |
Taxol | 180619_MC_11 | 12303 | 0.0297 | 65 | 302 | 10 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_4 | 367 | 0.0290 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00589 | 0.9131 |
Taxol | 180619_MC_11 | 11268 | 0.0303 | 68 | 276 | 12 | 4 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_5 | 344 | 0.0296 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00655 | 0.8766 |
Taxol | 180619_MC_11 | 11672 | 0.0293 | 56 | 288 | 13 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_6 | 344 | 0.0286 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00555 | 0.8911 |
Taxol | 180619_MC_12 | 12512 | 0.0301 | 112 | 268 | 10 | 15 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_7 | 380 | 0.0295 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00640 | 0.9201 |
Taxol | 180619_MC_12 | 13615 | 0.0266 | 94 | 270 | 10 | 18 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_8 | 364 | 0.0260 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00296 | 0.9560 |
Taxol | 180619_MC_12 | 13353 | 0.0283 | 94 | 287 | 12 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 2 | MCF10A-GM_9 | 381 | 0.0277 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00467 | 0.9477 |
Taxol | 180619_MC_10 | 3524 | 0.2086 | 273 | 519 | 5 | 21 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_1 | 792 | 0.1835 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.16043 | 0.4549 |
Taxol | 180619_MC_10 | 3888 | 0.1598 | 154 | 492 | 7 | 16 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_2 | 646 | 0.1425 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.11940 | 0.4866 |
Taxol | 180619_MC_10 | 3146 | 0.2069 | 203 | 490 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_3 | 693 | 0.1805 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.15744 | 0.4192 |
Taxol | 180619_MC_11 | 4024 | 0.1912 | 269 | 552 | 9 | 9 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_4 | 821 | 0.1695 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.14638 | 0.4978 |
Taxol | 180619_MC_11 | 3756 | 0.1618 | 175 | 461 | 12 | 12 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_5 | 636 | 0.1448 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.12173 | 0.4754 |
Taxol | 180619_MC_11 | 3333 | 0.1811 | 162 | 471 | 14 | 6 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_6 | 633 | 0.1596 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.13653 | 0.4373 |
Taxol | 180619_MC_12 | 3552 | 0.2090 | 328 | 483 | 5 | 15 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_7 | 811 | 0.1859 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.16281 | 0.4574 |
Taxol | 180619_MC_12 | 3801 | 0.1641 | 191 | 464 | 8 | 8 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_8 | 655 | 0.1470 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.12392 | 0.4792 |
Taxol | 180619_MC_12 | 3649 | 0.1907 | 295 | 457 | 13 | 11 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_9 | 752 | 0.1709 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.14780 | 0.4661 |
Taxol | 180619_MC_10 | 789 | 0.5558 | 161 | 367 | 3 | 9 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_1 | 528 | 0.4009 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.37784 | 0.0484 |
Taxol | 180619_MC_10 | 773 | 0.6127 | 190 | 400 | 4 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_2 | 590 | 0.4329 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.40979 | 0.0437 |
Taxol | 180619_MC_10 | 655 | 0.6484 | 238 | 341 | 4 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_3 | 579 | 0.4692 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.44613 | 0.0065 |
Taxol | 180619_MC_11 | 788 | 0.6087 | 206 | 399 | 5 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_4 | 605 | 0.4343 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.41124 | 0.0481 |
Taxol | 180619_MC_11 | 787 | 0.6842 | 296 | 445 | 11 | 11 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_5 | 741 | 0.4849 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.46187 | 0.0478 |
Taxol | 180619_MC_11 | 906 | 0.7083 | 352 | 539 | 13 | 5 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_6 | 891 | 0.4958 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.47275 | 0.0806 |
Taxol | 180619_MC_12 | 746 | 0.6211 | 286 | 355 | 3 | 14 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_7 | 641 | 0.4621 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.43907 | 0.0356 |
Taxol | 180619_MC_12 | 796 | 0.5848 | 230 | 370 | 12 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_8 | 600 | 0.4298 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.40673 | 0.0504 |
Taxol | 180619_MC_12 | 825 | 0.5805 | 274 | 364 | 14 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 2 | MCF10A-GM_9 | 638 | 0.4361 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.41302 | 0.0587 |