LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180615_MC_06 | 13050 | 0.0249 | 22 | 304 | 5 | 15 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 326 | 0.0244 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00097 | 1.0223 |
| Neratinib | 180615_MC_06 | 12274 | 0.0291 | 54 | 305 | 9 | 8 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 359 | 0.0284 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00502 | 0.9943 |
| Neratinib | 180615_MC_06 | 12426 | 0.0263 | 18 | 309 | 13 | 12 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 327 | 0.0256 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00224 | 0.9999 |
| Neratinib | 180615_MC_07 | 10921 | 0.0217 | 78 | 161 | 4 | 21 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 239 | 0.0214 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00198 | 0.9421 |
| Neratinib | 180615_MC_07 | 12469 | 0.0248 | 90 | 222 | 8 | 16 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 312 | 0.0244 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00101 | 1.0015 |
| Neratinib | 180615_MC_07 | 12915 | 0.0160 | 29 | 178 | 11 | 4 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 207 | 0.0158 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00762 | 1.0175 |
| Neratinib | 180615_MC_08 | 13350 | 0.0325 | 102 | 335 | 4 | 7 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 437 | 0.0317 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00830 | 1.0327 |
| Neratinib | 180615_MC_08 | 12583 | 0.0308 | 96 | 295 | 4 | 16 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 391 | 0.0301 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00674 | 1.0056 |
| Neratinib | 180615_MC_08 | 13403 | 0.0277 | 50 | 323 | 6 | 7 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 373 | 0.0271 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00368 | 1.0345 |
| Neratinib | 180615_MC_06 | 11277 | 0.0186 | 27 | 183 | 6 | 9 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 210 | 0.0183 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00512 | 0.9563 |
| Neratinib | 180615_MC_06 | 12916 | 0.0227 | 20 | 274 | 7 | 21 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 294 | 0.0223 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00114 | 1.0175 |
| Neratinib | 180615_MC_06 | 12215 | 0.0224 | 44 | 231 | 14 | 20 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 275 | 0.0220 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00138 | 0.9921 |
| Neratinib | 180615_MC_07 | 12181 | 0.0145 | 36 | 141 | 3 | 9 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 177 | 0.0143 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00908 | 0.9909 |
| Neratinib | 180615_MC_07 | 12678 | 0.0172 | 49 | 170 | 8 | 7 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 219 | 0.0170 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00642 | 1.0090 |
| Neratinib | 180615_MC_07 | 13078 | 0.0190 | 52 | 197 | 14 | 14 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 249 | 0.0187 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00471 | 1.0232 |
| Neratinib | 180615_MC_08 | 11758 | 0.0303 | 48 | 310 | 5 | 5 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 358 | 0.0295 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00615 | 0.9750 |
| Neratinib | 180615_MC_08 | 13503 | 0.0278 | 93 | 285 | 9 | 12 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 378 | 0.0272 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00383 | 1.0380 |
| Neratinib | 180615_MC_08 | 10796 | 0.0272 | 74 | 222 | 14 | 22 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 296 | 0.0267 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00329 | 0.9371 |
| Neratinib | 180615_MC_06 | 10885 | 0.0225 | 23 | 222 | 5 | 8 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_1 | 245 | 0.0220 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00139 | 0.9407 |
| Neratinib | 180615_MC_06 | 12619 | 0.0277 | 49 | 302 | 6 | 12 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_2 | 351 | 0.0271 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00366 | 1.0069 |
| Neratinib | 180615_MC_06 | 12153 | 0.0234 | 29 | 256 | 7 | 18 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_3 | 285 | 0.0229 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00048 | 0.9898 |
| Neratinib | 180615_MC_07 | 12952 | 0.0181 | 56 | 179 | 4 | 5 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_4 | 235 | 0.0178 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00558 | 1.0188 |
| Neratinib | 180615_MC_07 | 11704 | 0.0236 | 30 | 247 | 5 | 10 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_5 | 277 | 0.0231 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00028 | 0.9729 |
| Neratinib | 180615_MC_07 | 12581 | 0.0166 | 28 | 181 | 13 | 3 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_6 | 209 | 0.0163 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00706 | 1.0055 |
| Neratinib | 180615_MC_08 | 12422 | 0.0290 | 91 | 272 | 4 | 9 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_7 | 363 | 0.0284 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00499 | 0.9997 |