LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180615_MC_08 | 13250 | 0.0310 | 88 | 325 | 8 | 15 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_8 | 413 | 0.0302 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00683 | 1.0293 |
| Neratinib | 180615_MC_08 | 12223 | 0.0251 | 32 | 276 | 8 | 18 | Neratinib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_9 | 308 | 0.0246 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00118 | 0.9924 |
| Neratinib | 180615_MC_06 | 11622 | 0.0214 | 33 | 216 | 11 | 14 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_1 | 249 | 0.0210 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00242 | 0.9698 |
| Neratinib | 180615_MC_06 | 11978 | 0.0202 | 15 | 227 | 14 | 15 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_2 | 242 | 0.0198 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00359 | 0.9833 |
| Neratinib | 180615_MC_06 | 11492 | 0.0218 | 60 | 192 | 14 | 18 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_3 | 252 | 0.0215 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00194 | 0.9647 |
| Neratinib | 180615_MC_07 | 12901 | 0.0213 | 61 | 215 | 6 | 5 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_4 | 276 | 0.0209 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00245 | 1.0170 |
| Neratinib | 180615_MC_07 | 13002 | 0.0268 | 89 | 262 | 8 | 6 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_5 | 351 | 0.0263 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00289 | 1.0206 |
| Neratinib | 180615_MC_07 | 12890 | 0.0183 | 34 | 203 | 9 | 5 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_6 | 237 | 0.0181 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00534 | 1.0166 |
| Neratinib | 180615_MC_08 | 11833 | 0.0253 | 60 | 241 | 8 | 5 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_7 | 301 | 0.0248 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00141 | 0.9778 |
| Neratinib | 180615_MC_08 | 11548 | 0.0283 | 43 | 285 | 11 | 15 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_8 | 328 | 0.0276 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00422 | 0.9669 |
| Neratinib | 180615_MC_08 | 12694 | 0.0234 | 58 | 240 | 12 | 7 | Neratinib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_9 | 298 | 0.0229 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00046 | 1.0096 |
| Neratinib | 180615_MC_06 | 5262 | 0.0210 | 16 | 95 | 3 | 5 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_1 | 111 | 0.0207 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00274 | 0.6455 |
| Neratinib | 180615_MC_06 | 4556 | 0.0333 | 62 | 92 | 10 | 8 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_2 | 154 | 0.0327 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00930 | 0.5926 |
| Neratinib | 180615_MC_06 | 5263 | 0.0207 | 15 | 94 | 11 | 19 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_3 | 109 | 0.0203 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00311 | 0.6456 |
| Neratinib | 180615_MC_07 | 6575 | 0.0186 | 24 | 99 | 3 | 22 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_4 | 123 | 0.0184 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00503 | 0.7309 |
| Neratinib | 180615_MC_07 | 6389 | 0.0173 | 21 | 90 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_5 | 111 | 0.0171 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00632 | 0.7196 |
| Neratinib | 180615_MC_07 | 6846 | 0.0160 | 33 | 77 | 14 | 9 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_6 | 110 | 0.0158 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00758 | 0.7468 |
| Neratinib | 180615_MC_08 | 8625 | 0.0303 | 84 | 180 | 4 | 6 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_7 | 264 | 0.0297 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00630 | 0.8408 |
| Neratinib | 180615_MC_08 | 7184 | 0.0311 | 59 | 166 | 5 | 17 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_8 | 225 | 0.0304 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00697 | 0.7660 |
| Neratinib | 180615_MC_08 | 7451 | 0.0291 | 52 | 166 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 1 | MCF10A-GM_9 | 218 | 0.0284 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00503 | 0.7807 |
| Neratinib | 180615_MC_06 | 2478 | 0.0213 | 13 | 40 | 10 | 3 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_1 | 53 | 0.0209 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00246 | 0.3870 |
| Neratinib | 180615_MC_06 | 2315 | 0.0236 | 12 | 43 | 10 | 21 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_2 | 55 | 0.0232 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00019 | 0.3658 |
| Neratinib | 180615_MC_06 | 2580 | 0.0251 | 14 | 51 | 11 | 20 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_3 | 65 | 0.0246 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00118 | 0.3998 |
| Neratinib | 180615_MC_07 | 3834 | 0.0296 | 50 | 65 | 3 | 12 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_4 | 115 | 0.0291 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00572 | 0.5314 |
| Neratinib | 180615_MC_07 | 2822 | 0.0235 | 26 | 41 | 9 | 8 | Neratinib | 0.997999609 | treatment | 72 | 1 | MCF10A-GM_5 | 67 | 0.0232 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00021 | 0.4285 |