LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | 180615_MC_06 | 700 | 0.0928 | 54 | 16 | 8 | 20 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 70 | 0.0909 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06751 | 0.0411 |
| Etoposide | 180615_MC_07 | 653 | 0.1186 | 47 | 36 | 6 | 8 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 83 | 0.1128 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08937 | 0.0248 |
| Etoposide | 180615_MC_07 | 703 | 0.1658 | 57 | 69 | 14 | 4 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 126 | 0.1520 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.12859 | 0.0421 |
| Etoposide | 180615_MC_07 | 720 | 0.1124 | 54 | 33 | 14 | 17 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 87 | 0.1078 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08441 | 0.0477 |
| Etoposide | 180615_MC_08 | 784 | 0.1241 | 78 | 29 | 4 | 3 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 107 | 0.1201 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09669 | 0.0682 |
| Etoposide | 180615_MC_08 | 695 | 0.1514 | 78 | 39 | 8 | 10 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 117 | 0.1441 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.12069 | 0.0394 |
| Etoposide | 180615_MC_08 | 703 | 0.1081 | 46 | 35 | 12 | 4 | Etoposide | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 81 | 0.1033 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07992 | 0.0421 |
| Etoposide | 180615_MC_06 | 753 | 0.0756 | 27 | 32 | 4 | 15 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 59 | 0.0727 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04926 | 0.0585 |
| Etoposide | 180615_MC_06 | 747 | 0.1101 | 61 | 28 | 6 | 22 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 89 | 0.1065 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08306 | 0.0565 |
| Etoposide | 180615_MC_06 | 686 | 0.0726 | 30 | 22 | 10 | 7 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 52 | 0.0705 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04706 | 0.0363 |
| Etoposide | 180615_MC_07 | 724 | 0.1807 | 95 | 53 | 4 | 13 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 148 | 0.1697 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.14633 | 0.0491 |
| Etoposide | 180615_MC_07 | 702 | 0.0680 | 19 | 30 | 7 | 17 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 49 | 0.0652 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04185 | 0.0417 |
| Etoposide | 180615_MC_07 | 783 | 0.1038 | 55 | 32 | 14 | 16 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 87 | 0.1000 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07660 | 0.0679 |
| Etoposide | 180615_MC_08 | 733 | 0.2010 | 98 | 69 | 9 | 8 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 167 | 0.1856 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.16216 | 0.0520 |
| Etoposide | 180615_MC_08 | 765 | 0.1765 | 45 | 98 | 13 | 7 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 143 | 0.1575 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.13409 | 0.0623 |
| Etoposide | 180615_MC_08 | 826 | 0.1334 | 66 | 53 | 13 | 12 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 119 | 0.1259 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.10253 | 0.0809 |
| Neratinib | 180615_MC_06 | 11939 | 0.0226 | 33 | 238 | 3 | 13 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_1 | 271 | 0.0222 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00120 | 0.9818 |
| Neratinib | 180615_MC_06 | 12463 | 0.0259 | 48 | 276 | 8 | 22 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_2 | 324 | 0.0253 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00194 | 1.0012 |
| Neratinib | 180615_MC_06 | 11461 | 0.0231 | 27 | 238 | 11 | 17 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_3 | 265 | 0.0226 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00080 | 0.9635 |
| Neratinib | 180615_MC_07 | 12095 | 0.0193 | 42 | 192 | 3 | 17 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_4 | 234 | 0.0190 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00442 | 0.9877 |
| Neratinib | 180615_MC_07 | 13024 | 0.0157 | 23 | 182 | 14 | 10 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_5 | 205 | 0.0155 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00790 | 1.0213 |
| Neratinib | 180615_MC_07 | 12937 | 0.0210 | 61 | 212 | 14 | 11 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_6 | 273 | 0.0207 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00273 | 1.0183 |
| Neratinib | 180615_MC_08 | 12244 | 0.0288 | 74 | 281 | 4 | 5 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_7 | 355 | 0.0282 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00478 | 0.9932 |
| Neratinib | 180615_MC_08 | 12763 | 0.0224 | 32 | 254 | 11 | 22 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_8 | 286 | 0.0219 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00148 | 1.0121 |
| Neratinib | 180615_MC_08 | 11621 | 0.0237 | 47 | 230 | 13 | 16 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_9 | 277 | 0.0233 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00012 | 0.9697 |