Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
HCC38 GSK2334470
362.2276812
 0.7326 0.0411 1000.0000 -0.2309 0.3738 0.3294
0.006774661
SUM159PT SHP099
3294.604776
 0.8118 0.0447 1000.0000 0.1710 0.3511 0.3261
0.007206359
HCC1806 Ribociclib
168.232015049
 0.6251 0.1419 317.3038 -0.1285 0.3606 0.3213
0.00787309835959
SUM1315MO2 Rucaparib
17.80541463
 0.2942 0.3317 1000.0000 -0.3226 0.1236 0.3203
0.008018079
SUM1315MO2 SHP099
22.32790504
 0.4783 0.1197 419.3194 -1.0000 0.3746 0.3197
0.008107411
HCC1806 GSK2334470
44.5159354048
 0.8389 0.0198 86.1125 -0.5419 1.1127 0.3134
0.00908806432112
CAL-85-1 Rucaparib
15.9069887
 0.3496 0.2765 1000.0000 -0.6758 0.2065 0.3127
0.009204617
MDA-MB-453 SHP099
11.54207272
 0.7015 0.0178 14.3805 -1.0000 4.9966 0.3055
0.010499523
CAL-85-1 Ulixertinib
3.83746694
 0.2311 0.2960 72.1557 -1.0000 0.3744 0.3008
0.011412092
HCC1428 GSK2334470
0.261068206
 0.2500 0.4172 0.2322 0.2218 5.0000 0.2993
0.01172251
SUM1315MO2 AZD5363
inf
 0.5993 0.2010 0.1377 0.6619 0.3406 0.2935
0.013005042
MDA-MB-157 GSK2334470
76.35127426
 0.4545 0.1687 498.7726 -0.2137 0.1896 0.2637
0.021778256
CAL-51 GSK2334470
22.73047392
 0.8334 0.0336 53.5738 -0.9998 1.2813 0.2592
0.023515658
CAMA-1 Rucaparib
inf
 0.8528 0.1254 0.0108 0.8301 5.0000 0.2588
0.023653062
HCC1143 Rucaparib
212371.6019
 0.7856 0.0507 630.9562 0.3840 0.2511 0.2497
0.027576264
CAL-51 Senexin B
49184874.89
 0.7426 0.1286 1000.0000 0.4054 0.1541 0.2466
0.029016792
SUM1315MO2 Senexin B
inf
 0.7371 0.2113 0.5888 0.5399 0.2353 0.2333
0.036109414
HCC1428 Ulixertinib
0.227625258
 0.1375 0.4320 0.1734 0.1614 1.4315 0.2319
0.036949884
HCC1937 Rucaparib
inf
 0.7658 0.0636 0.0095 0.8675 5.0000 0.2293
0.038523875
HCC1428 Rucaparib
0.023670881
 -0.2500 0.7420 7.6534 -1.0000 0.1901 0.2290
0.038773048
SUM149PT SHP099
31.82140091
 0.7648 -0.0244 70.8992 -0.9990 1.3705 0.2286
0.038994512
MDA-MB-157 Ribociclib
inf
 0.5908 0.0808 0.0790 0.8320 5.0000 0.2263
0.040460682
SK-BR-3 Rucaparib
inf
 0.7324 0.1120 0.0074 0.8618 5.0000 0.2180
0.046276083
CAMA-1 GSK2334470
inf
 0.6437 -0.0125 0.0000 0.9959 0.0100 0.0000
0.05607765
T47D Rucaparib
inf
 0.8130 0.0415 0.0000 0.9307 0.0100 0.0000
0.073451061