Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
SK-BR-3 Rucaparib
inf
 0.7324 0.1120 0.0074 0.8618 5.0000 0.2180
0.046276083
MDA-MB-157 Ribociclib
inf
 0.5908 0.0808 0.0790 0.8320 5.0000 0.2263
0.040460682
SUM149PT SHP099
31.82140091
 0.7648 -0.0244 70.8992 -0.9990 1.3705 0.2286
0.038994512
HCC1428 Rucaparib
0.023670881
 -0.2500 0.7420 7.6534 -1.0000 0.1901 0.2290
0.038773048
HCC1937 Rucaparib
inf
 0.7658 0.0636 0.0095 0.8675 5.0000 0.2293
0.038523875
HCC1428 Ulixertinib
0.227625258
 0.1375 0.4320 0.1734 0.1614 1.4315 0.2319
0.036949884
SUM1315MO2 Senexin B
inf
 0.7371 0.2113 0.5888 0.5399 0.2353 0.2333
0.036109414
CAL-51 Senexin B
49184874.89
 0.7426 0.1286 1000.0000 0.4054 0.1541 0.2466
0.029016792
HCC1143 Rucaparib
212371.6019
 0.7856 0.0507 630.9562 0.3840 0.2511 0.2497
0.027576264
CAMA-1 Rucaparib
inf
 0.8528 0.1254 0.0108 0.8301 5.0000 0.2588
0.023653062
CAL-51 GSK2334470
22.73047392
 0.8334 0.0336 53.5738 -0.9998 1.2813 0.2592
0.023515658
MDA-MB-157 GSK2334470
76.35127426
 0.4545 0.1687 498.7726 -0.2137 0.1896 0.2637
0.021778256
SUM1315MO2 AZD5363
inf
 0.5993 0.2010 0.1377 0.6619 0.3406 0.2935
0.013005042
HCC1428 GSK2334470
0.261068206
 0.2500 0.4172 0.2322 0.2218 5.0000 0.2993
0.01172251
CAL-85-1 Ulixertinib
3.83746694
 0.2311 0.2960 72.1557 -1.0000 0.3744 0.3008
0.011412092
MDA-MB-453 SHP099
11.54207272
 0.7015 0.0178 14.3805 -1.0000 4.9966 0.3055
0.010499523
CAL-85-1 Rucaparib
15.9069887
 0.3496 0.2765 1000.0000 -0.6758 0.2065 0.3127
0.009204617
HCC1806 GSK2334470
44.5159354048
 0.8389 0.0198 86.1125 -0.5419 1.1127 0.3134
0.00908806432112
SUM1315MO2 SHP099
22.32790504
 0.4783 0.1197 419.3194 -1.0000 0.3746 0.3197
0.008107411
SUM1315MO2 Rucaparib
17.80541463
 0.2942 0.3317 1000.0000 -0.3226 0.1236 0.3203
0.008018079
HCC1806 Ribociclib
168.232015049
 0.6251 0.1419 317.3038 -0.1285 0.3606 0.3213
0.00787309835959
SUM159PT SHP099
3294.604776
 0.8118 0.0447 1000.0000 0.1710 0.3511 0.3261
0.007206359
HCC38 GSK2334470
362.2276812
 0.7326 0.0411 1000.0000 -0.2309 0.3738 0.3294
0.006774661
MDA-MB-436 GSK2334470
26.4830237
 0.7307 0.0123 64.9192 -0.9964 1.2226 0.3331
0.006324926
MDA-MB-361 Rucaparib
inf
 0.1133 0.3149 0.0128 0.5095 5.0000 0.3359
0.005993375