Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)
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| Cell | Small Molecule | GR50 | GRmax | GR_AOC | GEC50 | GRinf | GR Hill Coefficient | GR r2 | pval_GR |
|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | RO-3306 | -inf | 0.0360 | ||||||
| HCC1500 | MK 1775 | -inf | -0.9646 | ||||||
| MDA-MB-134-VI | GSK2334470 | -inf | 0.1440 | ||||||
| CAL-120 | THZ1 | -inf | -0.1577 | ||||||
| MDA-MB-361 | BMS-265246 | -inf | 0.1856 | 0.5730 | 0.0000 | 0.4334 | 0.0100 | 0.0000 | 0.160494567 |
| HCC1500 | RO-3306 | -inf | -0.9896 | ||||||
| HCC1500 | THZ1 | -inf | -0.9999 | ||||||
| MDA-MB-134-VI | Senexin B | -inf | 0.2609 | ||||||
| MDA-MB-134-VI | SHP099 | -inf | 0.8081 | ||||||
| HCC1500 | THZ531 | -inf | -0.9990 | ||||||
| HCC1500 | AZD6738 | -inf | -0.9469 | ||||||
| BT-549 | RO-3306 | -inf | -0.1143 | ||||||
| HCC70 | THZ1 | -inf | -0.8868 | ||||||
| HME1 | THZ1 | -inf | -0.3007 | ||||||
| SK-BR-3 | BMS-265246 | -inf | 0.0240 | ||||||
| SK-BR-3 | AZD6738 | -inf | -0.0818 | ||||||
| HCC1395 | AZD6738 | -inf | -0.3125 | ||||||
| MDA-MB-157 | MK 1775 | -inf | -0.8758 | ||||||
| HCC1419 | AZD6738 | -inf | 0.3243 | ||||||
| HCC1806 | BMS-265246 | -inf | -0.0075 | ||||||
| T47D | Ribociclib | -inf | 0.0709 | ||||||
| MCF7 | MK 1775 | -inf | -0.1007 | ||||||
| HCC1419 | LY3023414 | -inf | -0.6005 | ||||||
| CAL-120 | Alvocidib | -inf | -0.0679 | ||||||
| MCF7 | Alvocidib | -inf | -0.2526 |