Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
PDXHCI002 ML-323 72
17.8247031142
 0.1781 0.1858 109.9820 -1.0000 0.6037
Hs 578T SB1-F-22 72
48.629206693
 0.4746 0.0557 108.1899 -1.0000 1.3738
SK-BR-3 LDN57444 72
22.3408232354
 0.2285 0.1807 104.9983 -1.0000 0.7099
HCC1806 ML-323 72
51.7025090437
 0.5104 0.0851 100.5354 -0.3756 0.8426
SK-BR-3 IU1 72
206.741150231
 0.7547 0.0343 99.4820 0.2546 0.9732
HCC1954 SB1-F-22 72
57.8739615901
 0.5991 0.0409 99.2019 -1.0000 2.0387
BT-549 HY-17542 72
121.066157283
 0.9061 0.0081 95.3962 0.2549 2.9917
HCC1428 LDN57444 72
12.549009736
 -0.0136 0.2378 89.8320 -1.0000 0.5582
HCC1937 USP7-IN-1 72
65.8738738326
 0.8119 -0.0032 83.7971 -0.9000 4.2784
CAMA-1 ML-323 72
28.720597579
 0.2218 0.1069 83.5494 -1.0000 1.0288
BT-20 USP7-IN-1 72
67.2869814403
 0.7451 0.0229 80.6417 -0.3763 3.0994
CAMA-1 GW7647 72
51.1807184271
 0.5179 0.0238 80.0691 -0.9662 2.4039
MCF7 GW7647 72
67.0602654387
 0.8376 -0.0104 77.7420 -0.5174 4.8064
HCC1500 ML-323 72
22.8896968406
 0.1643 0.1263 77.3652 -1.0000 0.9021
HCC1419 USP7-IN-1 72
44.7550079567
 0.4088 0.0472 76.1826 -1.0000 2.0653
HCC1500 GW7647 72
42.1427904431
 0.1820 -0.0218 72.6766 -0.9087 1.9008
HCC1954 GW7647 72
53.2192077737
 0.5700 -0.0367 66.2968 -1.0000 5.0000
PDX1328 LDN57444 72
29.0838578196
 0.1664 0.1568 64.9414 -1.0000 1.3676
HCC1500 LDN57444 72
39.3689454794
 0.2463 0.0822 61.7679 -1.0000 2.4392
T47D ML-323 72
13.4276900688
 0.0649 0.2011 60.0348 -0.9911 0.7296
PDXHCI002 PB49673382 72
23.2849540906
 -0.0464 0.1415 59.6753 -1.0000 1.1674
HCC202 Doxycycline 72
41.0834372075
 0.2347 0.0694 58.6649 -1.0000 3.0839
HCC1419 Doxycycline 72
29.9947198826
 0.0713 0.0985 58.5488 -1.0000 1.6426
SK-BR-3 Doxycycline 72
30.0303971358
 0.1295 0.1243 58.5093 -1.0000 1.6472
MDA-MB-134-VI ML-323 72
45.5586104943
 0.3266 0.0626 58.1271 -1.0000 4.5093