Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1937 P22077
9.992797406
 0.3136 0.48118
HCC1937 P22077
31.6
 -0.6741 0.60192
HCC1937 P22077
50.0
 -0.5893 0.26403
HCC1937 PB49673382
0.009992797
 1.0824 -0.00474
HCC1937 PB49673382
0.0316
 0.9313 -0.00628
HCC1937 PB49673382
0.099927974
 0.9628 0.00590
HCC1937 PB49673382
0.316
 1.0175 -0.00598
HCC1937 PB49673382
0.999279741
 0.8889 -0.00498
HCC1937 PB49673382
3.16
 0.8410 0.01474
HCC1937 PB49673382
9.992797406
 0.3941 0.03001
HCC1937 PB49673382
31.6
 0.2750 0.04094
HCC1937 PB49673382
50.0
 0.2509 0.06219
HCC1937 Pimozide
0.009992797
 0.9575 -0.00479
HCC1937 Pimozide
0.0316
 0.9633 -0.00728
HCC1937 Pimozide
0.099927974
 0.9586 -0.00222
HCC1937 Pimozide
0.316
 0.9050 0.00089
HCC1937 Pimozide
0.999279741
 0.9506 0.01150
HCC1937 Pimozide
3.16
 0.8520 0.00554
HCC1937 Pimozide
9.992797406
 0.7835 0.01921
HCC1937 Pimozide
31.6
 -0.1729 0.40563
HCC1937 Pimozide
50.0
 -0.3172 0.45672
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9505 -0.00334
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9200 0.00989
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.1151 -0.00012
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0355 -0.00051