Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 1.0812 -0.00373
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.8155 0.00526
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9448 0.00275
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 1.1990 -0.00898
HCC1937 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9970 0.00108
HCC1937 SB1-F-21
0.009992797
 1.0555 0.01035
HCC1937 SB1-F-21
0.0316
 1.0193 -0.00496
HCC1937 SB1-F-21
0.099927974
 1.1107 -0.00378
HCC1937 SB1-F-21
0.316
 1.0508 -0.00436
HCC1937 SB1-F-21
0.999279741
 0.7395 0.07346
HCC1937 SB1-F-21
3.16
 -0.0104 0.34853
HCC1937 SB1-F-21
9.992797406
 -0.6275 0.67790
HCC1937 SB1-F-21
31.6
 -0.6548 0.60307
HCC1937 SB1-F-21
50.0
 -0.6311 0.47797
HCC1937 SB1-F-22
0.009992797
 0.8954 0.00561
HCC1937 SB1-F-22
0.0316
 0.9274 0.01587
HCC1937 SB1-F-22
0.099927974
 1.0067 0.01341
HCC1937 SB1-F-22
0.316
 0.9936 -0.00354
HCC1937 SB1-F-22
0.999279741
 0.9975 0.00284
HCC1937 SB1-F-22
3.16
 0.9721 0.00365
HCC1937 SB1-F-22
9.992797406
 0.9762 -0.00019
HCC1937 SB1-F-22
31.6
 0.7909 0.01502
HCC1937 SB1-F-22
50.0
 0.7329 0.04555
HCC1937 SJB2-043
0.00316
 1.0133 -0.00352
HCC1937 SJB2-043
0.009992797
 1.0788 -0.00399