Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1954 | MI-2 | 0.999279741 | 0.4436 | 0.32113 |
| HCC1954 | MI-2 | 3.16 | -0.6789 | 0.70634 |
| HCC1954 | MI-2 | 9.992797406 | -0.7158 | 0.70552 |
| HCC1954 | MI-2 | 31.6 | -0.7015 | 0.68414 |
| HCC1954 | MI-2 | 50.0 | -0.7113 | 0.46753 |
| HCC1954 | Mitoxantrone | 0.009992797 | 0.5253 | 0.11334 |
| HCC1954 | Mitoxantrone | 0.0316 | 0.3374 | 0.17276 |
| HCC1954 | Mitoxantrone | 0.099927974 | 0.0604 | 0.20885 |
| HCC1954 | Mitoxantrone | 0.316 | 0.0899 | 0.30497 |
| HCC1954 | Mitoxantrone | 0.999279741 | -0.1221 | 0.58484 |
| HCC1954 | Mitoxantrone | 3.16 | -0.6465 | 0.74984 |
| HCC1954 | Mitoxantrone | 9.992797406 | -0.7586 | 0.67920 |
| HCC1954 | Mitoxantrone | 31.6 | -0.6799 | 0.45381 |
| HCC1954 | Mitoxantrone | 50.0 | -0.3624 | 0.13523 |
| HCC1954 | ML-323 | 0.009992797 | 0.8600 | -0.00963 |
| HCC1954 | ML-323 | 0.0316 | 0.9641 | -0.01080 |
| HCC1954 | ML-323 | 0.099927974 | 0.9235 | 0.02303 |
| HCC1954 | ML-323 | 0.316 | 0.8472 | 0.03856 |
| HCC1954 | ML-323 | 0.999279741 | 1.0047 | -0.00560 |
| HCC1954 | ML-323 | 3.16 | 0.8594 | 0.02004 |
| HCC1954 | ML-323 | 9.992797406 | 0.8552 | -0.01607 |
| HCC1954 | ML-323 | 31.6 | 0.5984 | 0.03070 |
| HCC1954 | ML-323 | 50.0 | 0.5808 | -0.00278 |
| HCC1954 | Pevonedistat | 0.009992797 | 0.9547 | 0.02123 |
| HCC1954 | Pevonedistat | 0.0316 | 0.9471 | 0.01551 |