Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1937 | Mitoxantrone | 50.0 | -0.1720 | 0.16119 |
| HCC1937 | ML-323 | 0.009992797 | 1.0553 | -0.00511 |
| HCC1937 | ML-323 | 0.0316 | 1.0391 | -0.00428 |
| HCC1937 | ML-323 | 0.099927974 | 1.0090 | 0.00209 |
| HCC1937 | ML-323 | 0.316 | 1.0281 | 0.00830 |
| HCC1937 | ML-323 | 0.999279741 | 0.9589 | -0.00266 |
| HCC1937 | ML-323 | 3.16 | 0.9644 | 0.02057 |
| HCC1937 | ML-323 | 9.992797406 | 0.8263 | -0.00303 |
| HCC1937 | ML-323 | 31.6 | 0.7706 | -0.00290 |
| HCC1937 | ML-323 | 50.0 | 0.6194 | 0.00999 |
| HCC1937 | Pevonedistat | 0.009992797 | 0.9690 | 0.01537 |
| HCC1937 | Pevonedistat | 0.0316 | 0.8348 | 0.01649 |
| HCC1937 | Pevonedistat | 0.099927974 | 0.4295 | 0.03391 |
| HCC1937 | Pevonedistat | 0.316 | 0.0848 | 0.05355 |
| HCC1937 | Pevonedistat | 0.999279741 | -0.0096 | 0.07417 |
| HCC1937 | Pevonedistat | 3.16 | -0.0195 | 0.12070 |
| HCC1937 | Pevonedistat | 9.992797406 | -0.0465 | 0.16169 |
| HCC1937 | Pevonedistat | 31.6 | -0.0514 | 0.19896 |
| HCC1937 | Pevonedistat | 50.0 | -0.1081 | 0.16654 |
| HCC1937 | P22077 | 0.009992797 | 1.0128 | 0.00233 |
| HCC1937 | P22077 | 0.0316 | 0.9647 | -0.00361 |
| HCC1937 | P22077 | 0.099927974 | 1.0658 | -0.00357 |
| HCC1937 | P22077 | 0.316 | 1.0088 | -0.01201 |
| HCC1937 | P22077 | 0.999279741 | 1.0476 | -0.00063 |
| HCC1937 | P22077 | 3.16 | 0.9587 | 0.05780 |