Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | ML-323 | 9.992797406 | 0.7334 | 0.07778 |
| PDXHCI002 | ML-323 | 31.6 | 0.3941 | 0.14372 |
| PDXHCI002 | ML-323 | 50.0 | 0.1781 | 0.11780 |
| PDXHCI002 | Pevonedistat | 0.009992797 | 1.0465 | 0.03712 |
| PDXHCI002 | Pevonedistat | 0.0316 | 0.6396 | 0.13961 |
| PDXHCI002 | Pevonedistat | 0.099927974 | -0.0359 | 0.21156 |
| PDXHCI002 | Pevonedistat | 0.316 | -0.3450 | 0.25809 |
| PDXHCI002 | Pevonedistat | 0.999279741 | -0.4773 | 0.25429 |
| PDXHCI002 | Pevonedistat | 3.16 | -0.5457 | 0.33713 |
| PDXHCI002 | Pevonedistat | 9.992797406 | -0.5546 | 0.35857 |
| PDXHCI002 | Pevonedistat | 31.6 | -0.5207 | 0.38245 |
| PDXHCI002 | Pevonedistat | 50.0 | -0.5062 | 0.09274 |
| PDXHCI002 | P22077 | 0.009992797 | 1.0501 | -0.00116 |
| PDXHCI002 | P22077 | 0.0316 | 0.8341 | 0.00736 |
| PDXHCI002 | P22077 | 0.099927974 | 1.0700 | 0.00139 |
| PDXHCI002 | P22077 | 0.316 | 1.0434 | -0.00146 |
| PDXHCI002 | P22077 | 0.999279741 | 1.0400 | -0.00793 |
| PDXHCI002 | P22077 | 3.16 | 0.8383 | 0.01009 |
| PDXHCI002 | P22077 | 9.992797406 | 0.5853 | 0.06435 |
| PDXHCI002 | P22077 | 31.6 | -0.3555 | 0.40908 |
| PDXHCI002 | P22077 | 50.0 | -0.5061 | 0.58467 |
| PDXHCI002 | PB49673382 | 0.009992797 | 1.0103 | -0.00046 |
| PDXHCI002 | PB49673382 | 0.0316 | 0.9217 | -0.00667 |
| PDXHCI002 | PB49673382 | 0.099927974 | 0.9386 | 0.00647 |
| PDXHCI002 | PB49673382 | 0.316 | 0.9717 | -0.00863 |