Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
PDX1328 Pimozide
50.0
 -0.8952 0.52399
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.7617 -0.00017
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.8445 0.01334
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9674 0.00768
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.1186 -0.00558
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9598 -0.00754
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 1.0656 -0.00235
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.7620 -0.00280
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9911 -0.01248
PDX1328 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.1413 -0.00335
PDX1328 SB1-F-21
0.009992797
 0.7846 0.01119
PDX1328 SB1-F-21
0.0316
 1.1970 -0.00781
PDX1328 SB1-F-21
0.099927974
 1.0722 -0.01065
PDX1328 SB1-F-21
0.316
 0.8003 0.01595
PDX1328 SB1-F-21
0.999279741
 0.3551 0.08393
PDX1328 SB1-F-21
3.16
 -0.2531 0.32072
PDX1328 SB1-F-21
9.992797406
 -0.9263 0.61803
PDX1328 SB1-F-21
31.6
 -0.9783 0.64669
PDX1328 SB1-F-21
50.0
 -0.9869 0.46911
PDX1328 SB1-F-22
0.009992797
 0.9195 0.01383
PDX1328 SB1-F-22
0.0316
 0.9916 0.01273
PDX1328 SB1-F-22
0.099927974
 1.1721 0.00387
PDX1328 SB1-F-22
0.316
 1.0235 0.00806
PDX1328 SB1-F-22
0.999279741
 2.0701 -0.00837
PDX1328 SB1-F-22
3.16
 1.2112 0.00746