Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
PDXHCI002 PB49673382
0.999279741
 1.0103 -0.00964
PDXHCI002 PB49673382
3.16
 1.0108 -0.01788
PDXHCI002 PB49673382
9.992797406
 0.5816 -0.00305
PDXHCI002 PB49673382
31.6
 0.6015 -0.00663
PDXHCI002 PB49673382
50.0
 -0.0464 0.14643
PDXHCI002 Pimozide
0.009992797
 1.0800 0.00041
PDXHCI002 Pimozide
0.0316
 0.9950 0.00283
PDXHCI002 Pimozide
0.099927974
 0.9736 0.00306
PDXHCI002 Pimozide
0.316
 0.8011 0.02704
PDXHCI002 Pimozide
0.999279741
 0.8051 0.02337
PDXHCI002 Pimozide
3.16
 0.6732 0.06057
PDXHCI002 Pimozide
9.992797406
 -0.0512 0.29031
PDXHCI002 Pimozide
31.6
 -0.4607 0.58939
PDXHCI002 Pimozide
50.0
 -0.4762 0.60385
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.7921 0.00818
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.5778 0.09220
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0936 -0.00553
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0232 -0.00524
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 1.0800 0.09927
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.6285 -0.00647
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.8916 0.00002
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9950 -0.00297
PDXHCI002 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.1325 -0.03164
PDXHCI002 SB1-F-21
0.009992797
 1.0146 -0.00224
PDXHCI002 SB1-F-21
0.0316
 1.1432 -0.01086