Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | LDN57444 | 50.0 | 0.3570 | 0.02833 |
| PDXHCI002 | MI-2 | 0.009992797 | 1.1966 | 0.00145 |
| PDXHCI002 | MI-2 | 0.0316 | 0.9032 | -0.00674 |
| PDXHCI002 | MI-2 | 0.099927974 | 1.1427 | -0.00041 |
| PDXHCI002 | MI-2 | 0.316 | 0.9083 | 0.00674 |
| PDXHCI002 | MI-2 | 0.999279741 | 0.8945 | 0.16191 |
| PDXHCI002 | MI-2 | 3.16 | 0.0978 | 0.47595 |
| PDXHCI002 | MI-2 | 9.992797406 | -0.4799 | 0.55913 |
| PDXHCI002 | MI-2 | 31.6 | -0.4502 | 0.56430 |
| PDXHCI002 | MI-2 | 50.0 | -0.4498 | 0.12841 |
| PDXHCI002 | Mitoxantrone | 0.009992797 | -0.0781 | 0.26987 |
| PDXHCI002 | Mitoxantrone | 0.0316 | -0.1639 | 0.22439 |
| PDXHCI002 | Mitoxantrone | 0.099927974 | -0.1546 | 0.18471 |
| PDXHCI002 | Mitoxantrone | 0.316 | -0.3525 | 0.37104 |
| PDXHCI002 | Mitoxantrone | 0.999279741 | -0.6339 | 0.68222 |
| PDXHCI002 | Mitoxantrone | 3.16 | -0.4178 | 0.48939 |
| PDXHCI002 | Mitoxantrone | 9.992797406 | -0.4253 | 0.44449 |
| PDXHCI002 | Mitoxantrone | 31.6 | -0.4550 | 0.44759 |
| PDXHCI002 | Mitoxantrone | 50.0 | -0.5642 | 0.46604 |
| PDXHCI002 | ML-323 | 0.009992797 | 1.0420 | -0.00321 |
| PDXHCI002 | ML-323 | 0.0316 | 1.0010 | -0.00284 |
| PDXHCI002 | ML-323 | 0.099927974 | 0.9580 | 0.00246 |
| PDXHCI002 | ML-323 | 0.316 | 0.9511 | 0.00621 |
| PDXHCI002 | ML-323 | 0.999279741 | 0.8901 | 0.01697 |
| PDXHCI002 | ML-323 | 3.16 | 0.6582 | 0.07659 |