Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDXHCI002 | HY-50737A | 0.0316 | 1.0573 | 0.00129 |
| PDXHCI002 | HY-50737A | 0.099927974 | 0.9992 | 0.00440 |
| PDXHCI002 | HY-50737A | 0.316 | 0.9926 | 0.00353 |
| PDXHCI002 | HY-50737A | 0.999279741 | 0.9793 | -0.00341 |
| PDXHCI002 | HY-50737A | 3.16 | 0.9823 | 0.01917 |
| PDXHCI002 | HY-50737A | 9.992797406 | 0.4884 | 0.16964 |
| PDXHCI002 | HY-50737A | 31.6 | -0.0341 | 0.23139 |
| PDXHCI002 | HY-50737A | 50.0 | -0.3785 | 0.29605 |
| PDXHCI002 | IU1 | 0.009992797 | 0.9615 | -0.00135 |
| PDXHCI002 | IU1 | 0.0316 | 1.1113 | -0.00841 |
| PDXHCI002 | IU1 | 0.099927974 | 1.0725 | -0.01034 |
| PDXHCI002 | IU1 | 0.316 | 0.8209 | 0.06801 |
| PDXHCI002 | IU1 | 0.999279741 | 0.9707 | 0.00488 |
| PDXHCI002 | IU1 | 3.16 | 0.7967 | 0.01639 |
| PDXHCI002 | IU1 | 9.992797406 | 0.9515 | 0.03626 |
| PDXHCI002 | IU1 | 31.6 | 0.7347 | 0.04533 |
| PDXHCI002 | IU1 | 50.0 | 0.7669 | 0.01266 |
| PDXHCI002 | LDN57444 | 0.009992797 | 0.9359 | 0.00354 |
| PDXHCI002 | LDN57444 | 0.0316 | 0.9560 | -0.00062 |
| PDXHCI002 | LDN57444 | 0.099927974 | 0.9395 | -0.00084 |
| PDXHCI002 | LDN57444 | 0.316 | 0.5309 | 0.10901 |
| PDXHCI002 | LDN57444 | 0.999279741 | 0.9772 | -0.00140 |
| PDXHCI002 | LDN57444 | 3.16 | 1.0572 | -0.01284 |
| PDXHCI002 | LDN57444 | 9.992797406 | 0.8698 | -0.00686 |
| PDXHCI002 | LDN57444 | 31.6 | 0.6484 | 0.07799 |