Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1328 | Mitoxantrone | 0.316 | -0.2360 | 0.09811 |
| PDX1328 | Mitoxantrone | 0.999279741 | -0.3672 | 0.18706 |
| PDX1328 | Mitoxantrone | 3.16 | -0.9598 | 0.66161 |
| PDX1328 | Mitoxantrone | 9.992797406 | -0.9633 | 0.67402 |
| PDX1328 | Mitoxantrone | 31.6 | -0.9642 | 0.64921 |
| PDX1328 | Mitoxantrone | 50.0 | -0.9611 | 0.50079 |
| PDX1328 | ML-323 | 0.009992797 | 0.9717 | 0.00683 |
| PDX1328 | ML-323 | 0.0316 | 0.9548 | 0.00120 |
| PDX1328 | ML-323 | 0.099927974 | 1.1410 | 0.00604 |
| PDX1328 | ML-323 | 0.316 | 1.1384 | -0.00277 |
| PDX1328 | ML-323 | 0.999279741 | 0.6826 | 0.00748 |
| PDX1328 | ML-323 | 3.16 | 0.7045 | 0.01396 |
| PDX1328 | ML-323 | 9.992797406 | 0.7991 | -0.01517 |
| PDX1328 | ML-323 | 31.6 | 1.0189 | 0.00082 |
| PDX1328 | ML-323 | 50.0 | 0.7525 | -0.02205 |
| PDX1328 | Pevonedistat | 0.009992797 | 1.2957 | -0.00209 |
| PDX1328 | Pevonedistat | 0.0316 | 2.2642 | -0.00673 |
| PDX1328 | Pevonedistat | 0.099927974 | 4.1452 | -0.05106 |
| PDX1328 | Pevonedistat | 0.316 | 3.7848 | -0.04757 |
| PDX1328 | Pevonedistat | 0.999279741 | 1.1759 | 0.01805 |
| PDX1328 | Pevonedistat | 3.16 | -0.1611 | 0.10883 |
| PDX1328 | Pevonedistat | 9.992797406 | -0.5075 | 0.22321 |
| PDX1328 | Pevonedistat | 31.6 | -0.6824 | 0.30911 |
| PDX1328 | Pevonedistat | 50.0 | -0.7089 | 0.21309 |
| PDX1328 | P22077 | 0.009992797 | 0.9954 | 0.01506 |