Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-549 | ML-323 | 0.099927974 | 0.9850 | 0.00239 |
| BT-549 | ML-323 | 0.316 | 0.9898 | 0.00285 |
| BT-549 | ML-323 | 0.999279741 | 0.9600 | 0.00101 |
| BT-549 | ML-323 | 3.16 | 0.8889 | 0.00726 |
| BT-549 | ML-323 | 9.992797406 | 0.8268 | 0.00798 |
| BT-549 | ML-323 | 31.6 | 0.6856 | 0.02099 |
| BT-549 | ML-323 | 50.0 | 0.5763 | 0.03976 |
| BT-549 | Pevonedistat | 0.009992797 | 0.9780 | 0.01371 |
| BT-549 | Pevonedistat | 0.0316 | 0.9814 | 0.03991 |
| BT-549 | Pevonedistat | 0.099927974 | 0.7141 | 0.12437 |
| BT-549 | Pevonedistat | 0.316 | 0.3149 | 0.19853 |
| BT-549 | Pevonedistat | 0.999279741 | 0.0394 | 0.32413 |
| BT-549 | Pevonedistat | 3.16 | -0.1137 | 0.42619 |
| BT-549 | Pevonedistat | 9.992797406 | -0.2089 | 0.42325 |
| BT-549 | Pevonedistat | 31.6 | -0.2444 | 0.48430 |
| BT-549 | Pevonedistat | 50.0 | -0.2452 | 0.36009 |
| BT-549 | P22077 | 0.009992797 | 0.9899 | -0.00410 |
| BT-549 | P22077 | 0.0316 | 0.9949 | -0.00102 |
| BT-549 | P22077 | 0.099927974 | 0.9791 | 0.00226 |
| BT-549 | P22077 | 0.316 | 1.0054 | -0.00551 |
| BT-549 | P22077 | 0.999279741 | 1.0176 | -0.00358 |
| BT-549 | P22077 | 3.16 | 1.0106 | 0.00252 |
| BT-549 | P22077 | 9.992797406 | 0.8558 | 0.16251 |
| BT-549 | P22077 | 31.6 | -0.1547 | 0.34934 |
| BT-549 | P22077 | 50.0 | -0.2638 | 0.16185 |