Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
BT-20 Pimozide
0.999279741
 0.9652 0.02110
BT-20 Pimozide
3.16
 0.9835 0.00887
BT-20 Pimozide
9.992797406
 0.6110 0.02490
BT-20 Pimozide
31.6
 -0.7844 0.67881
BT-20 Pimozide
50.0
 -0.7818 0.67774
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9513 -0.00544
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.8957 0.01830
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9770 0.01747
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0038 0.01226
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9794 0.01143
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9054 0.01684
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9478 0.02910
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 1.0460 0.00274
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0522 -0.00108
BT-20 SB1-F-21
0.009992797
 1.0088 -0.00476
BT-20 SB1-F-21
0.0316
 1.1249 -0.02129
BT-20 SB1-F-21
0.099927974
 1.0508 -0.03800
BT-20 SB1-F-21
0.316
 1.0432 0.04497
BT-20 SB1-F-21
0.999279741
 -0.2090 0.38807
BT-20 SB1-F-21
3.16
 -0.6093 0.55402
BT-20 SB1-F-21
9.992797406
 -0.6752 0.57820
BT-20 SB1-F-21
31.6
 -0.7116 0.58227
BT-20 SB1-F-21
50.0
 -0.6851 0.33794
BT-20 SB1-F-22
0.009992797
 1.0022 -0.01249
BT-20 SB1-F-22
0.0316
 1.0079 0.00421