Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
BT-549 PB49673382
0.009992797
 0.9955 -0.00032
BT-549 PB49673382
0.0316
 0.9704 -0.00203
BT-549 PB49673382
0.099927974
 0.9651 0.00112
BT-549 PB49673382
0.316
 0.9602 -0.00476
BT-549 PB49673382
0.999279741
 0.9242 -0.00162
BT-549 PB49673382
3.16
 0.7557 0.01483
BT-549 PB49673382
9.992797406
 0.1131 0.11327
BT-549 PB49673382
31.6
 -0.0004 0.17972
BT-549 PB49673382
50.0
 0.0010 0.20885
BT-549 Pimozide
0.009992797
 0.9719 -0.00472
BT-549 Pimozide
0.0316
 0.9124 0.00299
BT-549 Pimozide
0.099927974
 0.9807 -0.00067
BT-549 Pimozide
0.316
 0.9513 -0.00358
BT-549 Pimozide
0.999279741
 0.9350 -0.00227
BT-549 Pimozide
3.16
 0.8822 0.00680
BT-549 Pimozide
9.992797406
 0.7057 0.05017
BT-549 Pimozide
31.6
 -0.2704 0.50490
BT-549 Pimozide
50.0
 -0.4203 0.65980
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9609 -0.00186
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9634 0.01096
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0054 0.00412
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9881 0.00245
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9976 0.00261
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9734 0.00232
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9902 0.00228