Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9516 -0.00012
BT-549 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9831 -0.00212
BT-549 SB1-F-21
0.009992797
 0.9556 -0.00416
BT-549 SB1-F-21
0.0316
 0.9955 0.00255
BT-549 SB1-F-21
0.099927974
 0.9351 0.00548
BT-549 SB1-F-21
0.316
 0.7811 0.02396
BT-549 SB1-F-21
0.999279741
 0.3652 0.09115
BT-549 SB1-F-21
3.16
 0.0708 0.18420
BT-549 SB1-F-21
9.992797406
 -0.1275 0.22940
BT-549 SB1-F-21
31.6
 -0.1943 0.27350
BT-549 SB1-F-21
50.0
 -0.2236 0.20726
BT-549 SB1-F-22
0.009992797
 1.0006 0.00077
BT-549 SB1-F-22
0.0316
 0.9967 -0.00192
BT-549 SB1-F-22
0.099927974
 1.0107 -0.00343
BT-549 SB1-F-22
0.316
 0.9995 0.00432
BT-549 SB1-F-22
0.999279741
 0.9920 0.00391
BT-549 SB1-F-22
3.16
 0.9985 0.00119
BT-549 SB1-F-22
9.992797406
 0.9439 0.00722
BT-549 SB1-F-22
31.6
 0.8394 0.01076
BT-549 SB1-F-22
50.0
 0.8206 0.02570
BT-549 SJB2-043
0.00316
 0.9940 -0.00253
BT-549 SJB2-043
0.009992797
 1.0312 -0.00313
BT-549 SJB2-043
0.0316
 0.9932 0.00208
BT-549 SJB2-043
0.099927974
 0.9565 0.00420
BT-549 SJB2-043
0.316
 0.9370 0.05103