Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
---|---|---|---|---|
BT-549 | LDN57444 | 0.999279741 | 0.9807 | -0.00015 |
BT-549 | LDN57444 | 3.16 | 0.9820 | 0.00229 |
BT-549 | LDN57444 | 9.992797406 | 0.9253 | 0.03684 |
BT-549 | LDN57444 | 31.6 | 0.3422 | 0.17286 |
BT-549 | LDN57444 | 50.0 | -0.0929 | 0.25387 |
BT-549 | MI-2 | 0.009992797 | 1.0167 | -0.00129 |
BT-549 | MI-2 | 0.0316 | 0.9652 | 0.00042 |
BT-549 | MI-2 | 0.099927974 | 1.0166 | -0.00109 |
BT-549 | MI-2 | 0.316 | 0.9230 | 0.07201 |
BT-549 | MI-2 | 0.999279741 | -0.1998 | 0.59009 |
BT-549 | MI-2 | 3.16 | -0.5623 | 0.63657 |
BT-549 | MI-2 | 9.992797406 | -0.4034 | 0.63813 |
BT-549 | MI-2 | 31.6 | -0.4518 | 0.64287 |
BT-549 | MI-2 | 50.0 | -0.4294 | 0.51866 |
BT-549 | Mitoxantrone | 0.009992797 | 0.8436 | 0.07056 |
BT-549 | Mitoxantrone | 0.0316 | 0.4903 | 0.14421 |
BT-549 | Mitoxantrone | 0.099927974 | 0.1583 | 0.17374 |
BT-549 | Mitoxantrone | 0.316 | -0.0157 | 0.21955 |
BT-549 | Mitoxantrone | 0.999279741 | -0.0682 | 0.36952 |
BT-549 | Mitoxantrone | 3.16 | -0.2002 | 0.61389 |
BT-549 | Mitoxantrone | 9.992797406 | -0.4496 | 0.74655 |
BT-549 | Mitoxantrone | 31.6 | -0.5149 | 0.70189 |
BT-549 | Mitoxantrone | 50.0 | -0.3393 | 0.27711 |
BT-549 | ML-323 | 0.009992797 | 0.9867 | -0.00121 |
BT-549 | ML-323 | 0.0316 | 1.0005 | 0.00103 |