Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-361 | HY-17542 | 0.999279741 | 1.0725 | NaN |
| MDA-MB-361 | Trifluoperazine | 0.0316 | 0.5162 | NaN |
| MDA-MB-361 | Doxycycline | 0.009992797 | 0.4003 | NaN |
| MDA-MB-361 | SJB2-043 | 0.316 | 0.9755 | NaN |
| MDA-MB-134-VI | Pevonedistat | 0.999279741 | -0.0248 | NaN |
| MDA-MB-134-VI | Mitoxantrone | 0.999279741 | -0.8709 | NaN |
| PDX1258 | P22077 | 0.316 | 1.0422 | NaN |
| Hs 578T | Mitoxantrone | 31.6 | -0.6749 | 0.86171 |
| MCF7 | Mitoxantrone | 31.6 | -0.7067 | 0.85879 |
| SK-BR-3 | Mitoxantrone | 9.992797406 | -0.7151 | 0.84844 |
| MDA-MB-134-VI | Mitoxantrone | 3.16 | -0.9842 | 0.84544 |
| SK-BR-3 | P22077 | 31.6 | -0.7339 | 0.84468 |
| HCC1419 | Mitoxantrone | 9.992797406 | -0.6974 | 0.84438 |
| SK-BR-3 | Mitoxantrone | 31.6 | -0.7263 | 0.83766 |
| Hs 578T | Mitoxantrone | 9.992797406 | -0.5916 | 0.83659 |
| SK-BR-3 | Trifluoperazine | 50.0 | -0.7359 | 0.83498 |
| SK-BR-3 | P22077 | 50.0 | -0.7151 | 0.83185 |
| SK-BR-3 | MI-2 | 9.992797406 | -0.6986 | 0.82102 |
| SK-BR-3 | Trifluoperazine | 31.6 | -0.7087 | 0.81524 |
| SK-BR-3 | MI-2 | 31.6 | -0.7413 | 0.81476 |
| BT-549 | Trifluoperazine | 31.6 | -0.3289 | 0.81320 |
| MDA-MB-134-VI | Mitoxantrone | 9.992797406 | -0.9693 | 0.81198 |
| SK-BR-3 | SJB3-019A | 50.0 | -0.7085 | 0.81177 |
| CAMA-1 | Mitoxantrone | 9.992797406 | -0.7131 | 0.80627 |
| HCC1428 | SJB3-019A | 3.16 | -0.8040 | 0.80308 |