Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1328 | SB1-F-21 | 50.0 | -0.9869 | 0.46911 |
| MDA-MB-134-VI | Mitoxantrone | 3.16 | -0.9842 | 0.84544 |
| PDX1328 | Trifluoperazine | 31.6 | -0.9795 | 0.63306 |
| PDX1328 | Trifluoperazine | 50.0 | -0.9791 | 0.63142 |
| PDX1328 | SB1-F-21 | 31.6 | -0.9783 | 0.64669 |
| PDX1328 | SJB3-019A | 31.6 | -0.9745 | 0.67538 |
| PDX1328 | HY-17541A | 50.0 | -0.9724 | 0.41348 |
| PDX1328 | SJB3-019A | 9.992797406 | -0.9722 | 0.66767 |
| MDA-MB-134-VI | Mitoxantrone | 9.992797406 | -0.9693 | 0.81198 |
| PDX1328 | Sepantronium | 50.0 | -0.9670 | 0.43410 |
| PDX1328 | Mitoxantrone | 31.6 | -0.9642 | 0.64921 |
| PDX1328 | Mitoxantrone | 9.992797406 | -0.9633 | 0.67402 |
| PDX1328 | Mitoxantrone | 50.0 | -0.9611 | 0.50079 |
| PDX1328 | Mitoxantrone | 3.16 | -0.9598 | 0.66161 |
| PDX1328 | SJB3-019A | 50.0 | -0.9595 | 0.63668 |
| PDX1328 | Sepantronium | 31.6 | -0.9588 | 0.64489 |
| PDX1328 | SJB3-019A | 0.999279741 | -0.9552 | 0.63308 |
| PDX1328 | SJB2-043 | 9.992797406 | -0.9550 | 0.63132 |
| PDX1328 | SJB2-043 | 31.6 | -0.9533 | 0.62932 |
| PDX1328 | P22077 | 50.0 | -0.9510 | 0.61407 |
| PDX1328 | SJB2-043 | 3.16 | -0.9510 | 0.63990 |
| PDX1328 | HBX19818 | 50.0 | -0.9490 | 0.67514 |
| MDA-MB-361 | Mitoxantrone | 50.0 | -0.9488 | 0.78637 |
| PDX1328 | SJB3-019A | 3.16 | -0.9461 | 0.61252 |
| PDX1328 | Sepantronium | 9.992797406 | -0.9459 | 0.62445 |