Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-231 | SJB2-043 | 0.00316 | 1.0048 | -0.00518 |
| MCF 10A | SJB2-043 | 0.00316 | 0.9899 | -0.00102 |
| HCC1806 | SJB2-043 | 0.00316 | 0.9759 | -0.00245 |
| MDA-MB-134-VI | SJB2-043 | 0.00316 | 0.6271 | -0.00505 |
| PDXHCI002 | SJB2-043 | 0.00316 | 0.9402 | -0.01284 |
| MDA-MB-361 | SJB2-043 | 0.00316 | 1.4230 | -0.00432 |
| CAMA-1 | SJB2-043 | 0.00316 | 0.9697 | -0.00023 |
| HCC1500 | SJB2-043 | 0.00316 | 0.9407 | -0.00346 |
| HCC202 | SJB2-043 | 0.00316 | 1.0115 | 0.00586 |
| MCF7 | SJB2-043 | 0.00316 | 1.0191 | -0.00258 |
| PDX1258 | SJB2-043 | 0.00316 | 1.0377 | -0.00249 |
| PDX1328 | SJB2-043 | 0.00316 | 0.9223 | 0.00063 |
| SK-BR-3 | SJB2-043 | 0.00316 | 0.9073 | 0.00446 |
| T47D | SJB2-043 | 0.00316 | 1.0157 | -0.00667 |
| BT-20 | SJB2-043 | 0.00316 | 1.1694 | -0.08846 |
| BT-549 | SJB2-043 | 0.00316 | 0.9940 | -0.00253 |
| HCC1419 | SJB2-043 | 0.00316 | 0.8831 | -0.00304 |
| HCC1428 | SJB2-043 | 0.00316 | 0.8875 | -0.01187 |
| HCC1937 | SJB2-043 | 0.00316 | 1.0133 | -0.00352 |
| HCC1954 | SJB2-043 | 0.00316 | 0.9618 | -0.02219 |
| Hs 578T | SJB2-043 | 0.00316 | 0.7977 | 0.00281 |
| BT-20 | 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | 0.009992797 | 0.9513 | -0.00544 |
| BT-20 | HY-50737A | 0.009992797 | 1.0087 | -0.00007 |
| BT-20 | SB1-F-21 | 0.009992797 | 1.0088 | -0.00476 |
| BT-20 | PB49673382 | 0.009992797 | 0.9483 | 0.00110 |