Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
MCF7 Vorinostat
HDAC
Misc
0.54198
 -0.1752 0.3494 0.0792 1.1946
0.72813
0.99735
HCC1419 Vorinostat
HDAC
Misc
1.735
 -0.2557 0.1917 0.0407 2.1116
2.1704
0.99173
MDA-MB-134-VI Vorinostat
HDAC
Misc
2.4577
 -0.5014 0.1748 0.0365 5.0000
2.8258
0.99386
PDX1258 Vorinostat
HDAC
Misc
1.5746
 -0.0232 0.2113 0.0249 1.3725
1.8225
0.99287
CAL-120 Vorinostat
HDAC
Misc
1.3545
 -0.2281 0.2409 0.0682 1.2739
2.1265
0.9951
T47D Vorinostat
HDAC
Misc
1.8007
 -0.1567 0.1750 0.0409 2.2684
2.0704
0.99157
HCC1937 Vorinostat
HDAC
Misc
1.9099
 -0.0085 0.1933 0.0353 1.4929
2.1786
0.99505
MDA-MB-468 Vorinostat
HDAC
Misc
1.5734
 -0.1191 0.2172 0.0608 1.9840
1.8053
0.99971
MDA-MB-231 Vorinostat
HDAC
Misc
1.2388
 -0.3848 0.2821 0.1116 1.7685
1.7699
0.99365
Hs 578T Vorinostat
HDAC
Misc
0.90288
 -0.1689 0.2728 0.1049 2.2431
1.0225
0.99568
BT-549 Vorinostat
HDAC
Misc
2.3739
 0.1131 0.1887 0.0291 0.8756
3.9571
0.99525
HME1 Vorinostat
HDAC
Misc
3.0223
 0.0551 0.1529 0.0150 1.2382
4.3407
0.99434
CAMA-1 Vorinostat
HDAC
Misc
0.88364
 -0.4902 0.3827 0.1366 1.5106
1.4957
0.98509
CAL-51 Vorinostat
HDAC
Misc
1.8294
 -0.0506 0.1862 0.0337 1.4510
2.2081
0.98967
HCC1500 Vorinostat
HDAC
Misc
0.95606
 -0.5960 0.3173 0.1165 1.0951
2.5286
0.99617