Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 Vorinostat
3.1623
HDAC
Misc
 0.4187 0.08655
BT-549 Vorinostat
10.0
HDAC
Misc
 0.1131 0.16461
BT-549 Luminespib
0.0001
HSP90
Misc
 1.0256 0.00500
BT-549 Luminespib
0.00031623
HSP90
Misc
 1.0068 0.00291
BT-549 Luminespib
0.001
HSP90
Misc
 0.9893 0.00583
BT-549 Luminespib
0.0031623
HSP90
Misc
 0.9554 0.01432
BT-549 Luminespib
0.01
HSP90
Misc
 -0.0556 0.29094
BT-549 Luminespib
0.031623
HSP90
Misc
 -0.0722 0.17722
BT-549 Luminespib
0.1
HSP90
Misc
 -0.0792 0.18586
BT-549 Luminespib
0.31623
HSP90
Misc
 -0.1028 0.19512
BT-549 Luminespib
1.0
HSP90
Misc
 -0.1064 0.20394
BT-549 A-1210477
0.001
Mcl-1
Misc
 0.9937 -0.00156
BT-549 A-1210477
0.0031623
Mcl-1
Misc
 1.0042 0.00177
BT-549 A-1210477
0.01
Mcl-1
Misc
 0.9684 0.00918
BT-549 A-1210477
0.031623
Mcl-1
Misc
 0.9914 -0.00041
BT-549 A-1210477
0.1
Mcl-1
Misc
 0.9877 0.00665
BT-549 A-1210477
0.31623
Mcl-1
Misc
 0.9783 0.00059
BT-549 A-1210477
1.0
Mcl-1
Misc
 1.0193 0.00302
BT-549 A-1210477
3.1623
Mcl-1
Misc
 1.0107 -0.00597
BT-549 A-1210477
10.0
Mcl-1
Misc
 0.9540 0.00299
BT-549 Olaparib
0.001
PARP
Misc
 1.0319 -0.00258
BT-549 Olaparib
0.0031623
PARP
Misc
 0.9891 0.00719
BT-549 Olaparib
0.01
PARP
Misc
 1.0168 0.00346
BT-549 Olaparib
0.031623
PARP
Misc
 1.0193 0.00481
BT-549 Olaparib
0.1
PARP
Misc
 0.9544 0.00978