Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 Saracatinib
0.001
SRC
MAPK/nRTK
 1.0337 0.00263
BT-549 Saracatinib
0.0031623
SRC
MAPK/nRTK
 0.9928 -0.00624
BT-549 Saracatinib
0.01
SRC
MAPK/nRTK
 1.0320 -0.00320
BT-549 Saracatinib
0.031623
SRC
MAPK/nRTK
 1.0304 -0.00331
BT-549 Saracatinib
0.1
SRC
MAPK/nRTK
 1.0089 -0.00214
BT-549 Saracatinib
0.31623
SRC
MAPK/nRTK
 1.0423 -0.00882
BT-549 Saracatinib
1.0
SRC
MAPK/nRTK
 0.9926 -0.00224
BT-549 Saracatinib
3.1623
SRC
MAPK/nRTK
 0.8276 0.00363
BT-549 Saracatinib
10.0
SRC
MAPK/nRTK
 0.5558 0.03329
BT-549 ABT-737
0.001
Bcl2/XL
Misc
 1.0573 -0.00717
BT-549 ABT-737
0.0031623
Bcl2/XL
Misc
 1.0193 -0.00050
BT-549 ABT-737
0.01
Bcl2/XL
Misc
 1.0546 0.00245
BT-549 ABT-737
0.031623
Bcl2/XL
Misc
 1.0688 0.01009
BT-549 ABT-737
0.1
Bcl2/XL
Misc
 1.0339 0.00131
BT-549 ABT-737
0.31623
Bcl2/XL
Misc
 1.0422 -0.00074
BT-549 ABT-737
1.0
Bcl2/XL
Misc
 0.9897 0.01055
BT-549 ABT-737
3.1623
Bcl2/XL
Misc
 1.0016 0.01775
BT-549 ABT-737
10.0
Bcl2/XL
Misc
 0.9359 0.02239
BT-549 Vorinostat
0.001
HDAC
Misc
 0.9835 -0.00943
BT-549 Vorinostat
0.0031623
HDAC
Misc
 1.0122 0.00489
BT-549 Vorinostat
0.01
HDAC
Misc
 0.9929 -0.00562
BT-549 Vorinostat
0.031623
HDAC
Misc
 1.0165 0.00457
BT-549 Vorinostat
0.1
HDAC
Misc
 0.9070 -0.00670
BT-549 Vorinostat
0.31623
HDAC
Misc
 0.8883 0.00602
BT-549 Vorinostat
1.0
HDAC
Misc
 0.7061 0.01686