Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
HCC38 | Cisplatin | 3.1623 | Chemo | Chemotherapy | 0.1078 | 0.36522 |
HCC38 | Cisplatin | 10.0 | Chemo | Chemotherapy | -0.1031 | 0.38118 |
HCC38 | Doxorubicin | 0.00031623 | Chemo | Chemotherapy | 1.0083 | 0.00558 |
HCC38 | Doxorubicin | 0.001 | Chemo | Chemotherapy | 0.9735 | 0.01321 |
HCC38 | Doxorubicin | 0.0031623 | Chemo | Chemotherapy | 0.9101 | 0.03096 |
HCC38 | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.4574 | 0.19501 |
HCC38 | Doxorubicin | 0.031623 | Chemo | Chemotherapy | -0.0617 | 0.33780 |
HCC38 | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.1768 | 0.41364 |
HCC38 | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.2588 | 0.44019 |
HCC38 | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.4061 | 0.55717 |
HCC38 | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.3683 | 0.59119 |
HCC38 | Taxol | 0.0001 | Chemo | Chemotherapy | 0.9325 | 0.02367 |
HCC38 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0364 | 0.01684 |
HCC38 | Taxol | 0.001 | Chemo | Chemotherapy | 0.7220 | 0.11105 |
HCC38 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.0089 | 0.34722 |
HCC38 | Taxol | 0.01 | Chemo | Chemotherapy | -0.1731 | 0.40043 |
HCC38 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.2077 | 0.37660 |
HCC38 | Taxol | 0.1 | Chemo | Chemotherapy | -0.2402 | 0.41561 |
HCC38 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.2046 | 0.35151 |
HCC38 | Taxol | 1.0 | Chemo | Chemotherapy | -0.3078 | 0.43898 |
HCC38 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9324 | 0.01134 |
HCC38 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.8150 | 0.04373 |
HCC38 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.2553 | 0.34106 |
HCC38 | Topotecan | 0.031667 | Topo I | Chemotherapy | -0.1016 | 0.46193 |
HCC38 | Topotecan | 0.1 | Topo I | Chemotherapy | -0.3243 | 0.50128 |