Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HCC38 Cabozantinib
0.31623
VEGFR2/MET
RTK
 1.0510 -0.01823
HCC38 Cabozantinib
1.0
VEGFR2/MET
RTK
 1.1234 -0.00476
HCC38 Cabozantinib
3.1623
VEGFR2/MET
RTK
 0.9835 -0.00654
HCC38 Cabozantinib
10.0
VEGFR2/MET
RTK
 0.3009 0.20270
HCC70 Abemaciclib
0.001
CDK4/6
Cell cycle
 1.0572 -0.00186
HCC70 Abemaciclib
0.0031623
CDK4/6
Cell cycle
 1.3213 -0.01140
HCC70 Abemaciclib
0.01
CDK4/6
Cell cycle
 1.2307 -0.00284
HCC70 Abemaciclib
0.031623
CDK4/6
Cell cycle
 1.1572 -0.01029
HCC70 Abemaciclib
0.1
CDK4/6
Cell cycle
 1.1428 -0.01908
HCC70 Abemaciclib
0.31623
CDK4/6
Cell cycle
 1.0890 -0.01642
HCC70 Abemaciclib
1.0
CDK4/6
Cell cycle
 0.8631 -0.00302
HCC70 Abemaciclib
3.1623
CDK4/6
Cell cycle
 -0.0768 0.17081
HCC70 Abemaciclib
10.0
CDK4/6
Cell cycle
 -0.8264 0.64288
HCC70 Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0366 0.00073
HCC70 Palbociclib
0.001
CDK4/6
Cell cycle
 1.0735 0.00757
HCC70 Palbociclib
0.0031623
CDK4/6
Cell cycle
 1.0888 -0.00706
HCC70 Palbociclib
0.01
CDK4/6
Cell cycle
 1.0868 0.00536
HCC70 Palbociclib
0.031623
CDK4/6
Cell cycle
 1.1144 -0.00125
HCC70 Palbociclib
0.1
CDK4/6
Cell cycle
 0.9546 0.00612
HCC70 Palbociclib
0.31623
CDK4/6
Cell cycle
 1.0338 -0.01225
HCC70 Palbociclib
1.0
CDK4/6
Cell cycle
 1.1035 -0.00058
HCC70 Palbociclib
3.1623
CDK4/6
Cell cycle
 0.9361 -0.00999
HCC70 AZD7762
0.001
CHK1/2
Cell cycle
 1.2110 0.00026
HCC70 AZD7762
0.0031623
CHK1/2
Cell cycle
 1.3706 -0.00299
HCC70 AZD7762
0.01
CHK1/2
Cell cycle
 1.1356 0.02091