Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-549 Olaparib
0.31623
PARP
Misc
 0.9316 0.00425
BT-549 Olaparib
1.0
PARP
Misc
 0.8777 0.01235
BT-549 Olaparib
3.1623
PARP
Misc
 0.8983 0.01703
BT-549 Olaparib
10.0
PARP
Misc
 0.5432 0.06053
BT-549 Bleomycin
0.0010833
Radiation
Misc
 0.9658 0.00644
BT-549 Bleomycin
0.0033333
Radiation
Misc
 0.9513 0.00907
BT-549 Bleomycin
0.01
Radiation
Misc
 0.9199 0.02635
BT-549 Bleomycin
0.031667
Radiation
Misc
 0.8410 0.05398
BT-549 Bleomycin
0.1
Radiation
Misc
 0.6722 0.10782
BT-549 Bleomycin
0.31623
Radiation
Misc
 0.3726 0.25245
BT-549 Bleomycin
1.0
Radiation
Misc
 0.0695 0.31127
BT-549 Bleomycin
3.1623
Radiation
Misc
 -0.0073 0.30193
BT-549 Bleomycin
10.0
Radiation
Misc
 -0.0141 0.28605
BT-549 Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9859 0.00538
BT-549 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 0.9846 0.00473
BT-549 Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9963 0.00129
BT-549 Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.9311 0.00802
BT-549 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.8348 0.00416
BT-549 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.7689 0.00574
BT-549 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.7136 0.00345
BT-549 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.6422 0.02457
BT-549 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.4956 0.02987
BT-549 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 1.0385 0.00525
BT-549 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 1.0216 0.00102
BT-549 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 1.0001 0.00808