Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-20 Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.0060 0.22860
BT-20 Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 -0.2891 0.53722
BT-20 Everolimus
0.001
mTOR1
PI3K/mTOR
 0.4153 0.11605
BT-20 Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.4128 0.08851
BT-20 Everolimus
0.01
mTOR1
PI3K/mTOR
 0.3772 0.11263
BT-20 Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.4106 0.09818
BT-20 Everolimus
0.1
mTOR1
PI3K/mTOR
 0.3800 0.10152
BT-20 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.4138 0.07177
BT-20 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.4369 0.07155
BT-20 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.4209 0.06403
BT-20 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.3900 0.07549
BT-20 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0214 -0.00216
BT-20 INK-128
0.001
mTORC1/2
PI3K/mTOR
 0.9904 0.00063
BT-20 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.8691 0.00564
BT-20 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.5772 0.05094
BT-20 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.2381 0.12694
BT-20 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.1269 0.18623
BT-20 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.0917 0.19161
BT-20 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.0580 0.20414
BT-20 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 -0.0045 0.25901
BT-20 PF-4708671
0.001
p70S6K
PI3K/mTOR
 1.0440 0.00369
BT-20 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.1036 -0.00040
BT-20 PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.1177 0.00043
BT-20 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0436 0.00010
BT-20 PF-4708671
0.1
p70S6K
PI3K/mTOR
 1.0501 0.00433