Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF7 Vorinostat
1.0
HDAC
Misc
 0.2542 0.09077
MCF7 Vorinostat
3.1623
HDAC
Misc
 -0.0037 0.26078
MCF7 Vorinostat
10.0
HDAC
Misc
 -0.1752 0.33565
MCF7 Luminespib
0.0001
HSP90
Misc
 1.0129 -0.00003
MCF7 Luminespib
0.00031623
HSP90
Misc
 0.9727 0.00305
MCF7 Luminespib
0.001
HSP90
Misc
 1.0409 0.00149
MCF7 Luminespib
0.0031623
HSP90
Misc
 0.9326 0.00464
MCF7 Luminespib
0.01
HSP90
Misc
 0.4095 0.04179
MCF7 Luminespib
0.031623
HSP90
Misc
 0.0183 0.12225
MCF7 Luminespib
0.1
HSP90
Misc
 0.0015 0.14132
MCF7 Luminespib
0.31623
HSP90
Misc
 0.0117 0.12837
MCF7 Luminespib
1.0
HSP90
Misc
 0.0015 0.11483
MCF7 A-1210477
0.001
Mcl-1
Misc
 0.9825 -0.00133
MCF7 A-1210477
0.0031623
Mcl-1
Misc
 1.0351 -0.00197
MCF7 A-1210477
0.01
Mcl-1
Misc
 0.9785 0.00277
MCF7 A-1210477
0.031623
Mcl-1
Misc
 1.0279 0.00001
MCF7 A-1210477
0.1
Mcl-1
Misc
 1.0262 0.00285
MCF7 A-1210477
0.31623
Mcl-1
Misc
 1.0398 -0.00137
MCF7 A-1210477
1.0
Mcl-1
Misc
 0.9874 -0.00078
MCF7 A-1210477
3.1623
Mcl-1
Misc
 0.9772 -0.00131
MCF7 A-1210477
10.0
Mcl-1
Misc
 0.8774 0.00784
MCF7 Olaparib
0.001
PARP
Misc
 1.0065 0.00204
MCF7 Olaparib
0.0031623
PARP
Misc
 0.9889 0.00239
MCF7 Olaparib
0.01
PARP
Misc
 0.9747 0.00339
MCF7 Olaparib
0.031623
PARP
Misc
 0.9922 0.00000