Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
SUM159PT | A-1210477 | 0.01 | Mcl-1 | Misc | 1.0291 | -0.00081 |
SUM159PT | A-1210477 | 0.031623 | Mcl-1 | Misc | 1.0091 | -0.00052 |
SUM159PT | A-1210477 | 0.1 | Mcl-1 | Misc | 1.0119 | 0.00065 |
SUM159PT | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0210 | -0.00347 |
SUM159PT | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0163 | -0.00219 |
SUM159PT | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0026 | -0.00060 |
SUM159PT | A-1210477 | 10.0 | Mcl-1 | Misc | 0.7796 | 0.02753 |
SUM159PT | Olaparib | 0.001 | PARP | Misc | 0.9966 | -0.00243 |
SUM159PT | Olaparib | 0.0031623 | PARP | Misc | 1.0005 | 0.00010 |
SUM159PT | Olaparib | 0.01 | PARP | Misc | 0.9912 | -0.00139 |
SUM159PT | Olaparib | 0.031623 | PARP | Misc | 1.0007 | 0.00009 |
SUM159PT | Olaparib | 0.1 | PARP | Misc | 0.9801 | 0.00019 |
SUM159PT | Olaparib | 0.31623 | PARP | Misc | 0.9825 | -0.00019 |
SUM159PT | Olaparib | 1.0 | PARP | Misc | 0.9691 | 0.00129 |
SUM159PT | Olaparib | 3.1623 | PARP | Misc | 0.9356 | 0.00271 |
SUM159PT | Olaparib | 10.0 | PARP | Misc | 0.7244 | 0.00975 |
SUM159PT | Bleomycin | 0.0010833 | Radiation | Misc | 0.9745 | -0.00149 |
SUM159PT | Bleomycin | 0.0033333 | Radiation | Misc | 0.9750 | -0.01123 |
SUM159PT | Bleomycin | 0.01 | Radiation | Misc | 0.9270 | 0.00357 |
SUM159PT | Bleomycin | 0.031667 | Radiation | Misc | 0.8499 | 0.03975 |
SUM159PT | Bleomycin | 0.1 | Radiation | Misc | 0.7057 | 0.07816 |
SUM159PT | Bleomycin | 0.31623 | Radiation | Misc | 0.4939 | 0.18584 |
SUM159PT | Bleomycin | 1.0 | Radiation | Misc | 0.2028 | 0.35017 |
SUM159PT | Bleomycin | 3.1623 | Radiation | Misc | 0.0608 | 0.43149 |
SUM159PT | Bleomycin | 10.0 | Radiation | Misc | -0.0577 | 0.43590 |