Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM159PT ABT-737
0.1
Bcl2/XL
Misc
 1.0125 0.00490
SUM159PT ABT-737
0.31623
Bcl2/XL
Misc
 0.9923 0.00561
SUM159PT ABT-737
1.0
Bcl2/XL
Misc
 0.9887 0.00483
SUM159PT ABT-737
3.1623
Bcl2/XL
Misc
 0.9538 0.01048
SUM159PT ABT-737
10.0
Bcl2/XL
Misc
 0.6822 0.02432
SUM159PT Vorinostat
0.001
HDAC
Misc
 1.0122 0.00307
SUM159PT Vorinostat
0.0031623
HDAC
Misc
 1.0089 0.00392
SUM159PT Vorinostat
0.01
HDAC
Misc
 1.0024 0.00187
SUM159PT Vorinostat
0.031623
HDAC
Misc
 1.0031 0.00388
SUM159PT Vorinostat
0.1
HDAC
Misc
 0.9809 0.00415
SUM159PT Vorinostat
0.31623
HDAC
Misc
 0.9244 0.00571
SUM159PT Vorinostat
1.0
HDAC
Misc
 0.7057 0.00732
SUM159PT Vorinostat
3.1623
HDAC
Misc
 0.3605 0.04575
SUM159PT Vorinostat
10.0
HDAC
Misc
 0.1195 0.11844
SUM159PT Luminespib
0.0001
HSP90
Misc
 0.9807 0.00025
SUM159PT Luminespib
0.00031623
HSP90
Misc
 1.0083 0.00186
SUM159PT Luminespib
0.001
HSP90
Misc
 1.0031 0.00240
SUM159PT Luminespib
0.0031623
HSP90
Misc
 0.9603 0.00695
SUM159PT Luminespib
0.01
HSP90
Misc
 0.0821 0.26016
SUM159PT Luminespib
0.031623
HSP90
Misc
 -0.0305 0.42094
SUM159PT Luminespib
0.1
HSP90
Misc
 -0.0448 0.42156
SUM159PT Luminespib
0.31623
HSP90
Misc
 -0.0476 0.42996
SUM159PT Luminespib
1.0
HSP90
Misc
 -0.0317 0.39610
SUM159PT A-1210477
0.001
Mcl-1
Misc
 1.0124 -0.00002
SUM159PT A-1210477
0.0031623
Mcl-1
Misc
 1.0141 0.00264