Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM1315MO2 Pictilisib
0.001
pan PI3K
PI3K/mTOR
 0.9723 0.00350
SUM1315MO2 Pictilisib
0.0031623
pan PI3K
PI3K/mTOR
 0.8624 0.01384
SUM1315MO2 Pictilisib
0.01
pan PI3K
PI3K/mTOR
 0.8598 0.00103
SUM1315MO2 Pictilisib
0.031623
pan PI3K
PI3K/mTOR
 0.8216 0.01366
SUM1315MO2 Pictilisib
0.1
pan PI3K
PI3K/mTOR
 0.7189 0.02257
SUM1315MO2 Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.4960 0.03743
SUM1315MO2 Pictilisib
1.0
pan PI3K
PI3K/mTOR
 0.4205 0.05479
SUM1315MO2 Pictilisib
3.1623
pan PI3K
PI3K/mTOR
 0.3044 0.09911
SUM1315MO2 Pictilisib
10.0
pan PI3K
PI3K/mTOR
 0.1300 0.14368
SUM1315MO2 Ceritinib
0.001
ALK
RTK
 0.9376 -0.00476
SUM1315MO2 Ceritinib
0.0031623
ALK
RTK
 0.9858 0.00293
SUM1315MO2 Ceritinib
0.01
ALK
RTK
 0.9410 -0.00036
SUM1315MO2 Ceritinib
0.031623
ALK
RTK
 0.9427 -0.00579
SUM1315MO2 Ceritinib
0.1
ALK
RTK
 0.8874 0.00459
SUM1315MO2 Ceritinib
0.31623
ALK
RTK
 0.7009 0.01395
SUM1315MO2 Ceritinib
1.0
ALK
RTK
 0.3445 0.06307
SUM1315MO2 Ceritinib
3.1623
ALK
RTK
 -0.1962 0.12783
SUM1315MO2 Ceritinib
10.0
ALK
RTK
 -0.7650 0.67576
SUM1315MO2 Neratinib
0.00031623
EGFR/HER2
RTK
 1.0787 0.00154
SUM1315MO2 Neratinib
0.001
EGFR/HER2
RTK
 0.9627 0.00626
SUM1315MO2 Neratinib
0.0031623
EGFR/HER2
RTK
 0.9896 0.00888
SUM1315MO2 Neratinib
0.01
EGFR/HER2
RTK
 0.9031 0.00370
SUM1315MO2 Neratinib
0.031623
EGFR/HER2
RTK
 0.6708 0.01775
SUM1315MO2 Neratinib
0.1
EGFR/HER2
RTK
 0.5040 0.04302
SUM1315MO2 Neratinib
0.31623
EGFR/HER2
RTK
 0.2845 0.05900