Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SUM1315MO2 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.6495 0.02058
SUM1315MO2 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.4035 0.05260
SUM1315MO2 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.2390 0.08200
SUM1315MO2 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.0804 0.09721
SUM1315MO2 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.0955 0.10322
SUM1315MO2 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.0390 0.09835
SUM1315MO2 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 0.0256 0.13204
SUM1315MO2 PF-4708671
0.001
p70S6K
PI3K/mTOR
 1.0528 0.00977
SUM1315MO2 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.0099 0.01158
SUM1315MO2 PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.0310 0.00331
SUM1315MO2 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0299 -0.00229
SUM1315MO2 PF-4708671
0.1
p70S6K
PI3K/mTOR
 0.9893 -0.00099
SUM1315MO2 PF-4708671
0.31623
p70S6K
PI3K/mTOR
 0.8305 -0.00095
SUM1315MO2 PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.8514 0.01129
SUM1315MO2 PF-4708671
3.1623
p70S6K
PI3K/mTOR
 0.6539 0.00692
SUM1315MO2 PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.5951 0.01413
SUM1315MO2 Buparlisib
0.001
pan PI3K
PI3K/mTOR
 0.9540 0.00471
SUM1315MO2 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 1.0566 0.00615
SUM1315MO2 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 0.9859 0.00369
SUM1315MO2 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 0.8713 0.01062
SUM1315MO2 Buparlisib
0.1
pan PI3K
PI3K/mTOR
 0.7042 0.02052
SUM1315MO2 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.6689 0.02958
SUM1315MO2 Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.2206 0.14871
SUM1315MO2 Buparlisib
3.1623
pan PI3K
PI3K/mTOR
 -0.3042 0.43925
SUM1315MO2 Buparlisib
10.0
pan PI3K
PI3K/mTOR
 -0.3686 0.37110