Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 INK-128
3.1623
mTORC1/2
PI3K/mTOR
 0.1969 0.03486
HME1 PF-4708671
0.001
p70S6K
PI3K/mTOR
 1.0587 0.00033
HME1 PF-4708671
0.0031623
p70S6K
PI3K/mTOR
 1.0866 0.00075
HME1 PF-4708671
0.01
p70S6K
PI3K/mTOR
 1.1362 -0.00362
HME1 PF-4708671
0.031623
p70S6K
PI3K/mTOR
 1.0765 0.00981
HME1 PF-4708671
0.1
p70S6K
PI3K/mTOR
 0.9394 0.04131
HME1 PF-4708671
0.31623
p70S6K
PI3K/mTOR
 0.8228 0.08888
HME1 PF-4708671
1.0
p70S6K
PI3K/mTOR
 0.6859 0.13357
HME1 PF-4708671
3.1623
p70S6K
PI3K/mTOR
 0.5633 0.17981
HME1 PF-4708671
10.0
p70S6K
PI3K/mTOR
 0.4546 0.22018
HME1 Buparlisib
0.001
pan PI3K
PI3K/mTOR
 1.0111 0.00342
HME1 Buparlisib
0.0031623
pan PI3K
PI3K/mTOR
 1.0536 -0.00188
HME1 Buparlisib
0.01
pan PI3K
PI3K/mTOR
 1.0758 0.00029
HME1 Buparlisib
0.031623
pan PI3K
PI3K/mTOR
 1.0504 0.00016
HME1 Buparlisib
0.1
pan PI3K
PI3K/mTOR
 1.0183 -0.00138
HME1 Buparlisib
0.31623
pan PI3K
PI3K/mTOR
 0.9368 0.00095
HME1 Buparlisib
1.0
pan PI3K
PI3K/mTOR
 0.5782 0.04188
HME1 Buparlisib
3.1623
pan PI3K
PI3K/mTOR
 -0.0435 0.26682
HME1 Buparlisib
10.0
pan PI3K
PI3K/mTOR
 -0.2416 0.43276
HME1 Pictilisib
0.001
pan PI3K
PI3K/mTOR
 1.0160 0.00204
HME1 Pictilisib
0.0031623
pan PI3K
PI3K/mTOR
 1.0708 -0.00362
HME1 Pictilisib
0.01
pan PI3K
PI3K/mTOR
 1.0836 -0.00419
HME1 Pictilisib
0.031623
pan PI3K
PI3K/mTOR
 1.0620 -0.00204
HME1 Pictilisib
0.1
pan PI3K
PI3K/mTOR
 1.0267 -0.00122
HME1 Pictilisib
0.31623
pan PI3K
PI3K/mTOR
 0.9034 -0.00515