Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
HME1 Torin2
0.00031623
mTOR/ATM/ATR
PI3K/mTOR
 1.0897 -0.00162
HME1 Torin2
0.001
mTOR/ATM/ATR
PI3K/mTOR
 1.0483 -0.00063
HME1 Torin2
0.0031623
mTOR/ATM/ATR
PI3K/mTOR
 0.9259 0.00099
HME1 Torin2
0.01
mTOR/ATM/ATR
PI3K/mTOR
 0.6546 0.01181
HME1 Torin2
0.031623
mTOR/ATM/ATR
PI3K/mTOR
 0.4421 0.02120
HME1 Torin2
0.1
mTOR/ATM/ATR
PI3K/mTOR
 0.3169 0.04647
HME1 Torin2
0.31623
mTOR/ATM/ATR
PI3K/mTOR
 0.2245 0.06345
HME1 Torin2
1.0
mTOR/ATM/ATR
PI3K/mTOR
 0.0764 0.13877
HME1 Everolimus
0.001
mTOR1
PI3K/mTOR
 0.5368 0.04040
HME1 Everolimus
0.0031623
mTOR1
PI3K/mTOR
 0.6320 0.01605
HME1 Everolimus
0.01
mTOR1
PI3K/mTOR
 0.6666 0.01417
HME1 Everolimus
0.031623
mTOR1
PI3K/mTOR
 0.7072 0.00811
HME1 Everolimus
0.1
mTOR1
PI3K/mTOR
 0.6647 0.01377
HME1 Everolimus
0.31623
mTOR1
PI3K/mTOR
 0.6991 0.01013
HME1 Everolimus
1.0
mTOR1
PI3K/mTOR
 0.5375 0.02702
HME1 Everolimus
3.1623
mTOR1
PI3K/mTOR
 0.6077 0.02022
HME1 Everolimus
10.0
mTOR1
PI3K/mTOR
 0.4888 0.03539
HME1 INK-128
0.00031623
mTORC1/2
PI3K/mTOR
 1.0243 -0.00157
HME1 INK-128
0.001
mTORC1/2
PI3K/mTOR
 1.0296 0.00222
HME1 INK-128
0.0031623
mTORC1/2
PI3K/mTOR
 0.9754 0.00314
HME1 INK-128
0.01
mTORC1/2
PI3K/mTOR
 0.7782 0.01042
HME1 INK-128
0.031623
mTORC1/2
PI3K/mTOR
 0.4967 0.01487
HME1 INK-128
0.1
mTORC1/2
PI3K/mTOR
 0.3564 0.02238
HME1 INK-128
0.31623
mTORC1/2
PI3K/mTOR
 0.2894 0.02383
HME1 INK-128
1.0
mTORC1/2
PI3K/mTOR
 0.2599 0.03748