Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
MCF7 Doxorubicin
0.01
Chemo
Chemotherapy
 0.5842 0.03652
MCF7 Doxorubicin
0.031623
Chemo
Chemotherapy
 0.2156 0.06740
MCF7 Doxorubicin
0.1
Chemo
Chemotherapy
 0.0771 0.06013
MCF7 Doxorubicin
0.31623
Chemo
Chemotherapy
 0.0074 0.09109
MCF7 Doxorubicin
1.0
Chemo
Chemotherapy
 -0.2730 0.37605
MCF7 Doxorubicin
3.1623
Chemo
Chemotherapy
 -0.2856 0.27052
MCF7 Taxol
0.0001
Chemo
Chemotherapy
 0.7154 0.02464
MCF7 Taxol
0.00031623
Chemo
Chemotherapy
 0.9160 0.00338
MCF7 Taxol
0.001
Chemo
Chemotherapy
 0.6387 0.03335
MCF7 Taxol
0.0031623
Chemo
Chemotherapy
 0.2311 0.14510
MCF7 Taxol
0.01
Chemo
Chemotherapy
 -0.0356 0.23309
MCF7 Taxol
0.031623
Chemo
Chemotherapy
 -0.0637 0.25262
MCF7 Taxol
0.1
Chemo
Chemotherapy
 -0.0662 0.25516
MCF7 Taxol
0.31623
Chemo
Chemotherapy
 -0.1059 0.24200
MCF7 Taxol
1.0
Chemo
Chemotherapy
 -0.0995 0.24049
MCF7 Topotecan
0.0010833
Topo I
Chemotherapy
 0.9330 -0.00177
MCF7 Topotecan
0.0033333
Topo I
Chemotherapy
 0.6822 0.00833
MCF7 Topotecan
0.01
Topo I
Chemotherapy
 0.3112 0.08705
MCF7 Topotecan
0.031667
Topo I
Chemotherapy
 0.0342 0.04689
MCF7 Topotecan
0.1
Topo I
Chemotherapy
 0.0238 0.02792
MCF7 Topotecan
0.31623
Topo I
Chemotherapy
 0.0198 0.04156
MCF7 Topotecan
1.0
Topo I
Chemotherapy
 -0.0482 0.09322
MCF7 Topotecan
3.1623
Topo I
Chemotherapy
 -0.1545 0.27758
MCF7 Topotecan
10.0
Topo I
Chemotherapy
 -0.2711 0.51761
MCF7 Etoposide
0.0010833
Topo II
Chemotherapy
 0.9998 -0.00083