Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
CAMA-1 Taxol
0.31623
Chemo
Chemotherapy
 -0.4708 0.57926
CAMA-1 Taxol
1.0
Chemo
Chemotherapy
 -0.4944 0.58426
CAMA-1 Topotecan
0.0010833
Topo I
Chemotherapy
 0.7749 0.00508
CAMA-1 Topotecan
0.0033333
Topo I
Chemotherapy
 0.5453 0.03353
CAMA-1 Topotecan
0.01
Topo I
Chemotherapy
 0.0384 0.12277
CAMA-1 Topotecan
0.031667
Topo I
Chemotherapy
 -0.1717 0.15680
CAMA-1 Topotecan
0.1
Topo I
Chemotherapy
 -0.1246 0.20068
CAMA-1 Topotecan
0.31623
Topo I
Chemotherapy
 -0.2693 0.30034
CAMA-1 Topotecan
1.0
Topo I
Chemotherapy
 -0.2871 0.30418
CAMA-1 Topotecan
3.1623
Topo I
Chemotherapy
 -0.3059 0.31435
CAMA-1 Topotecan
10.0
Topo I
Chemotherapy
 -0.4230 0.45168
CAMA-1 Etoposide
0.0010833
Topo II
Chemotherapy
 0.9204 -0.00628
CAMA-1 Etoposide
0.0033333
Topo II
Chemotherapy
 1.0043 -0.00210
CAMA-1 Etoposide
0.01
Topo II
Chemotherapy
 1.0564 -0.00659
CAMA-1 Etoposide
0.031667
Topo II
Chemotherapy
 0.9455 0.00039
CAMA-1 Etoposide
0.1
Topo II
Chemotherapy
 0.6661 0.02215
CAMA-1 Etoposide
0.31623
Topo II
Chemotherapy
 0.1346 0.08738
CAMA-1 Etoposide
1.0
Topo II
Chemotherapy
 -0.1945 0.24922
CAMA-1 Etoposide
3.1623
Topo II
Chemotherapy
 -0.3802 0.45373
CAMA-1 Etoposide
10.0
Topo II
Chemotherapy
 -0.4476 0.53357
CAMA-1 Dasatinib
0.001
BCR/ABL
MAPK/nRTK
 0.9183 0.00002
CAMA-1 Dasatinib
0.0031623
BCR/ABL
MAPK/nRTK
 0.9440 0.00573
CAMA-1 Dasatinib
0.01
BCR/ABL
MAPK/nRTK
 0.8735 0.00440
CAMA-1 Dasatinib
0.031623
BCR/ABL
MAPK/nRTK
 0.8621 0.00302
CAMA-1 Dasatinib
0.1
BCR/ABL
MAPK/nRTK
 0.8928 -0.00716