Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D Vorinostat
0.001
HDAC
Misc
 1.0650 0.00067
T47D Vorinostat
0.0031623
HDAC
Misc
 1.0265 0.00024
T47D Vorinostat
0.01
HDAC
Misc
 1.0355 -0.00209
T47D Vorinostat
0.031623
HDAC
Misc
 1.1048 -0.00156
T47D Vorinostat
0.1
HDAC
Misc
 1.1136 0.00226
T47D Vorinostat
0.31623
HDAC
Misc
 1.1532 0.00107
T47D Vorinostat
1.0
HDAC
Misc
 0.7936 0.01302
T47D Vorinostat
3.1623
HDAC
Misc
 0.1479 0.07491
T47D Vorinostat
10.0
HDAC
Misc
 -0.1567 0.27999
T47D Luminespib
0.0001
HSP90
Misc
 1.0474 0.00019
T47D Luminespib
0.00031623
HSP90
Misc
 1.0934 -0.00022
T47D Luminespib
0.001
HSP90
Misc
 1.0613 0.00022
T47D Luminespib
0.0031623
HSP90
Misc
 0.9411 0.01164
T47D Luminespib
0.01
HSP90
Misc
 0.1359 0.02815
T47D Luminespib
0.031623
HSP90
Misc
 0.0968 0.04912
T47D Luminespib
0.1
HSP90
Misc
 0.0310 0.05327
T47D Luminespib
0.31623
HSP90
Misc
 0.0212 0.05315
T47D Luminespib
1.0
HSP90
Misc
 0.0367 0.05444
T47D A-1210477
0.001
Mcl-1
Misc
 1.0290 0.00098
T47D A-1210477
0.0031623
Mcl-1
Misc
 1.0873 0.00113
T47D A-1210477
0.01
Mcl-1
Misc
 1.0798 -0.00394
T47D A-1210477
0.031623
Mcl-1
Misc
 1.0117 0.00158
T47D A-1210477
0.1
Mcl-1
Misc
 0.9912 -0.00280
T47D A-1210477
0.31623
Mcl-1
Misc
 1.0109 -0.00165
T47D A-1210477
1.0
Mcl-1
Misc
 1.0271 0.00086