Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D A-1210477
3.1623
Mcl-1
Misc
 0.8752 0.00441
T47D A-1210477
10.0
Mcl-1
Misc
 0.5752 0.04873
T47D Olaparib
0.001
PARP
Misc
 1.0719 0.00086
T47D Olaparib
0.0031623
PARP
Misc
 0.9999 -0.00070
T47D Olaparib
0.01
PARP
Misc
 0.9902 -0.00332
T47D Olaparib
0.031623
PARP
Misc
 1.0966 -0.00271
T47D Olaparib
0.1
PARP
Misc
 1.0508 0.00208
T47D Olaparib
0.31623
PARP
Misc
 1.0475 0.00263
T47D Olaparib
1.0
PARP
Misc
 1.0028 -0.00109
T47D Olaparib
3.1623
PARP
Misc
 0.8281 -0.00042
T47D Olaparib
10.0
PARP
Misc
 0.5304 0.01618
T47D Bleomycin
0.0010833
Radiation
Misc
 0.9271 -0.00306
T47D Bleomycin
0.0033333
Radiation
Misc
 1.0060 -0.00344
T47D Bleomycin
0.01
Radiation
Misc
 0.9590 -0.00271
T47D Bleomycin
0.031667
Radiation
Misc
 0.7551 0.00532
T47D Bleomycin
0.1
Radiation
Misc
 0.7716 0.00981
T47D Bleomycin
0.31623
Radiation
Misc
 0.3533 0.02970
T47D Bleomycin
1.0
Radiation
Misc
 0.0769 0.03552
T47D Bleomycin
3.1623
Radiation
Misc
 -0.0051 0.04686
T47D Bleomycin
10.0
Radiation
Misc
 -0.0840 0.05337
T47D Ipatasertib
0.001
AKT
PI3K/mTOR
 0.9819 0.00130
T47D Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0666 0.00107
T47D Ipatasertib
0.01
AKT
PI3K/mTOR
 0.9092 0.00291
T47D Ipatasertib
0.031623
AKT
PI3K/mTOR
 0.8064 0.00219
T47D Ipatasertib
0.1
AKT
PI3K/mTOR
 0.5806 0.00422