Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
T47D Abemaciclib
0.0031623
CDK4/6
Cell cycle
 0.6048 0.00282
T47D Abemaciclib
0.01
CDK4/6
Cell cycle
 0.2620 0.01025
T47D Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.1058 0.01541
T47D Abemaciclib
0.1
CDK4/6
Cell cycle
 0.1609 0.00818
T47D Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.1159 0.01638
T47D Abemaciclib
1.0
CDK4/6
Cell cycle
 0.1568 0.01422
T47D Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.0494 0.06623
T47D Abemaciclib
10.0
CDK4/6
Cell cycle
 -0.0412 0.10529
T47D Palbociclib
0.00031623
CDK4/6
Cell cycle
 1.0495 0.00143
T47D Palbociclib
0.001
CDK4/6
Cell cycle
 1.0459 -0.00050
T47D Palbociclib
0.0031623
CDK4/6
Cell cycle
 1.0099 0.00184
T47D Palbociclib
0.01
CDK4/6
Cell cycle
 0.7784 0.00080
T47D Palbociclib
0.031623
CDK4/6
Cell cycle
 0.4646 0.00870
T47D Palbociclib
0.1
CDK4/6
Cell cycle
 0.2138 0.01362
T47D Palbociclib
0.31623
CDK4/6
Cell cycle
 0.1804 0.01826
T47D Palbociclib
1.0
CDK4/6
Cell cycle
 0.1166 0.01548
T47D Palbociclib
3.1623
CDK4/6
Cell cycle
 0.1307 0.00938
T47D AZD7762
0.001
CHK1/2
Cell cycle
 1.2145 -0.00469
T47D AZD7762
0.0031623
CHK1/2
Cell cycle
 1.2355 0.00015
T47D AZD7762
0.01
CHK1/2
Cell cycle
 1.3830 -0.00136
T47D AZD7762
0.031623
CHK1/2
Cell cycle
 1.2962 0.00114
T47D AZD7762
0.1
CHK1/2
Cell cycle
 1.2980 0.00257
T47D AZD7762
0.31623
CHK1/2
Cell cycle
 1.1810 0.00498
T47D AZD7762
1.0
CHK1/2
Cell cycle
 0.9057 0.01473
T47D AZD7762
3.1623
CHK1/2
Cell cycle
 0.2905 0.06193