Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| SUM149PT | Doxorubicin | 0.01 | Chemo | Chemotherapy | 0.4140 | 0.20859 |
| SUM149PT | Doxorubicin | 0.031623 | Chemo | Chemotherapy | -0.0371 | 0.31423 |
| SUM149PT | Doxorubicin | 0.1 | Chemo | Chemotherapy | -0.0616 | 0.18515 |
| SUM149PT | Doxorubicin | 0.31623 | Chemo | Chemotherapy | -0.0841 | 0.19898 |
| SUM149PT | Doxorubicin | 1.0 | Chemo | Chemotherapy | -0.2883 | 0.54780 |
| SUM149PT | Doxorubicin | 3.1623 | Chemo | Chemotherapy | -0.3172 | 0.64213 |
| SUM149PT | Taxol | 0.0001 | Chemo | Chemotherapy | 0.9760 | 0.01190 |
| SUM149PT | Taxol | 0.00031623 | Chemo | Chemotherapy | 0.9645 | 0.00671 |
| SUM149PT | Taxol | 0.001 | Chemo | Chemotherapy | 0.8332 | 0.05827 |
| SUM149PT | Taxol | 0.0031623 | Chemo | Chemotherapy | -0.0477 | 0.55176 |
| SUM149PT | Taxol | 0.01 | Chemo | Chemotherapy | -0.1548 | 0.60518 |
| SUM149PT | Taxol | 0.031623 | Chemo | Chemotherapy | -0.1732 | 0.50746 |
| SUM149PT | Taxol | 0.1 | Chemo | Chemotherapy | -0.2482 | 0.56020 |
| SUM149PT | Taxol | 0.31623 | Chemo | Chemotherapy | -0.2583 | 0.55990 |
| SUM149PT | Taxol | 1.0 | Chemo | Chemotherapy | -0.2558 | 0.57332 |
| SUM149PT | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9057 | 0.01212 |
| SUM149PT | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.7155 | 0.06212 |
| SUM149PT | Topotecan | 0.01 | Topo I | Chemotherapy | 0.2417 | 0.30860 |
| SUM149PT | Topotecan | 0.031667 | Topo I | Chemotherapy | -0.0577 | 0.51852 |
| SUM149PT | Topotecan | 0.1 | Topo I | Chemotherapy | -0.0346 | 0.49333 |
| SUM149PT | Topotecan | 0.31623 | Topo I | Chemotherapy | -0.0898 | 0.49810 |
| SUM149PT | Topotecan | 1.0 | Topo I | Chemotherapy | -0.1749 | 0.52064 |
| SUM149PT | Topotecan | 3.1623 | Topo I | Chemotherapy | -0.3127 | 0.65689 |
| SUM149PT | Topotecan | 10.0 | Topo I | Chemotherapy | -0.4596 | 0.76066 |
| SUM149PT | Etoposide | 0.0010833 | Topo II | Chemotherapy | 1.0287 | -0.00536 |